Results 131 to 140 of about 1,546,902 (293)

JDC-DA: An Unsupervised Target Domain Algorithm for Alzheimer’s Disease Diagnosis with Structural MRI Using Joint Domain and Category Dual Adaptation

open access: yesMathematics
Domain shift in multi-source MRI imaging data significantly degrades the performance of Alzheimer’s disease diagnostic models. This study aims to develop an effective unsupervised domain adaptation method to enhance diagnostic accuracy across different ...
Yuan Sui   +3 more
doaj   +1 more source

Novel Node Category Detection Under Subpopulation Shift

open access: yes
In real-world graph data, distribution shifts can manifest in various ways, such as the emergence of new categories and changes in the relative proportions of existing categories. It is often important to detect nodes of novel categories under such distribution shifts for safety or insight discovery purposes.
Chung, Hsing-Huan   +4 more
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Contrastive Mean-Shift Learning for Generalized Category Discovery

open access: yes2024 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR)
Accepted at CVPR ...
Choi, Sua, Kang, Dahyun, Cho, Minsu
openaire   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Effects of duration and other noise characteristics on the annoyance caused by aircraft-flyover noise [PDF]

open access: yes
A laboratory experiment was conducted to determine the effects of duration and other noise characteristics on the annoyance caused by aircraft-flyover noise.
Mccurdy, D. A., Powell, C. A.
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Spiritual relaxation therapy to improve sleep quality for nurses working shifts who experience sleep problems: a quasi-experimental study

open access: yesMedisains
Background: Impaired sleep quality is a common problem experienced by nurses working shifts, and if not treated properly, it can impact their work performance and overall health.
Sudigdo Dwi Prasetyo   +1 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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