Results 161 to 170 of about 1,977,169 (247)
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Estimating population change with a two-category shift-share model
Shift-share analysis is an accounting procedure that identifies three separate effects for regional employment change. But the analysis is ordinarily restricted to only one category: usually, industry employment.
Andreas Molin, Gordon F. Mulligan
core +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Perceptual adaptation to a novel accent: Phonetic category expansion or category shift?
Yevgeniy Vasilyevich Melguy, Keith Johnson; Perceptual adaptation to a novel accent: Phonetic category expansion or category shift?. J. Acoust. Soc. Am. 1 October 2022; 152 (4): 2090–2104.
Keith Johnson, Yevgeniy Melguy
core
Categorial shift: from description to theory and back again [PDF]
Language Sciences, 2019 Heyvaert, Liesbet +2 more
openaire +2 more sources
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
THE COUNTABILITY OF ENGLISH NOUNS: CATEGORY SHIFTS
, 2013 The noun is one of the most important sentence elements in grammar. Accordingly, it plays an important role. It occurs in various forms, but generally, we can say that in English language the nouns may be divided into a limited number of categories, which differ according to their meaning and grammatical use.
openaire +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source