Results 71 to 80 of about 1,546,902 (293)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
A New Look at the Old Race Language: Rethinking Race and Exclusion in Social Policy [PDF]
, 1993 This essay is an examination of the use of the notion “race current in American social science literature and public discourse. It argues that the current assumptions of “race are mistaken and lead to misunderstanding and misdirected social policy.
Ngin, ChorSwang
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
PERGESERAN BENTUK DAN MAKNA DALAM PENERJEMAHAN TEKS DRAMA MA'SĀTU ZAINAB KARYA ALI AHMAD BĀKATSĪR
CMES (Center of Middle Eastern Studies), 2017 This research discusses the kinds of form and meaning shift in the Ma'sātu Zainab drama text translation. The purposes of this research are to describe the kinds of form and meaning shift in the Ma'sātu Zainab drama text translation.
Ulfah Haniyatur Rofi‟ah, Muhammad Yunus Anis
doaj +1 more source
Dualities of artinian coalgebras with applications to noetherian complete algebras [PDF]
, 2010 A duality theorem of the bounded derived category of quasi-finite comodules over an artinian coalgebra is established. Let $A$ be a noetherian complete basic semiperfect algebra over an algebraically closed field, and $C$ be its dual coalgebra. If $A$ is
B. Torrecillas +4 more
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Noon at 9 to 5: Reflections on a Decade of Organizing [PDF]
, 1986 [Excerpt] As manufacturing jobs have been automated, shipped abroad and shut down for good, traditional sources of employment as well as union members have dried up, with severe effects for the labor movement.
Cameron, Cindia
core +1 more source
Category effects on stimulus estimation: Shifting and skewed frequency distributions [PDF]
Psychonomic Bulletin & Review, 2010 The category adjustment model (CAM) proposes that estimates of inexactly remembered stimuli are adjusted toward the central value of the category of which the stimuli are members. Adjusting estimates toward the average value of all category instances, properly weighted for memory uncertainty, maximizes the average accuracy of estimates.
Sean, Duffy +3 more
openaire +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source