Results 41 to 50 of about 18,890 (226)
Nature Communications, 2022 Catharanthus roseus is the source for anticancer drug vinblastine and other medicinal monoterpenoid indole alkaloids. Here the authors characterize an Fe/2OG dioxygenase, vindolinine synthase, which catalyzes an unusual redox-neutral reaction leading to ...
Jasmine Ga May Eng +5 more
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Revista Brasileira de Ciência do Solo, 2018 Catharanthus roseus (L) G. Don (Madagascar periwinkle) belongs to the Apocynaceace family and is widely spread throughout tropical and subtropical regions of the world.
Cecília Silva Monnerat +6 more
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Strictosidine activation in Apocynaceae: towards a "nuclear time bomb"? [PDF]
, 2010 Background The first two enzymatic steps of monoterpene indole alkaloid (MIA) biosynthetic pathway are catalysed by strictosidine synthase (STR) that condensates tryptamine and secologanin to form strictosidine and by strictosidine β-D-glucosidase (SGD ...
Guirimand Grégory +8 more
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Viruses infecting periwinkle (Catharanthus roseus L.) in Western Saudi Arabia
Phytopathologia Mediterranea, 2018 Periwinkle (Catharanthus roseus L.) is an ornamental plant widely grown in the Mecca region in the Kingdom of Saudi Arabia (KSA). Different symptoms similar to those induced by viruses (mosaic, vein clearing, mottling, yellowing, flower variegation ...
Esam ELBESHEHY +3 more
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Comparative study of the hypoglycemic and biochemical effects of Catharanthus roseus (Linn) g. apocynaceae (Madagascar periwinkle) and chlorpropamide (diabenese) on alloxan-induced diabetic rats [PDF]
, 2005 The effect of the aqueous extracts of Catharanthus roseus and chlorpropamide (Diabenese) on the levels of serum cholesterol, total protein, lipid peroxidation, blood glucose and liver enzymes were compared in alloxan-induced diabetic rats.
Iweala, E. E. J., Okeke, C. U.
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The ORCA2 transcription factor plays a key role in regulation of the terpenoid indole alkaloid pathway [PDF]
, 2013 Background: The terpenoid indole alkaloid (TIA) pathway leads to the production of pharmaceutically important drugs, such as the anticancer compounds vinblastine and vincristine.
Gibson, Susan +6 more
core +3 more sources
Nature Communications, 2021 Camptothecin is a monoterpene indole alkaloid with anti-tumor activity. Here, the authors assemble the genome of the camptothecin producing plant Camptotheca acuminata and provide insights into the evolutionary origin of camptothecin biosynthesis by ...
Minghui Kang +9 more
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Separations, 2023 The leaves of Catharanthus roseus (L.) G. Don contain a large number of diverse secondary metabolites, making them comparably complex. The Catharanthus genus has received increased interest from scientists in recent years due to its extensive ...
Jyoti Rani +4 more
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Current status of herbal and their future perspectives [PDF]
, 2007 Traditional medicine is the synthesis of therapeutic experience of generations of practicing physicians of indigenous systems of medicine. Throughout the history of mankind, many infectious diseases have been treated with herbals.
Ponnampalam Gopalakrishnakone +1 more
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Catharanthus roseus intoxication mimicking acute cholangitis
BMC Complementary Medicine and TherapiesBackground Catharanthus roseus, a Madagascar native flowering plant, is known for its glossy leaves and vibrant flowers, and its medicinal significance due to its alkaloid compounds.
Yoen Young Chuah +3 more
doaj +1 more source