Results 181 to 190 of about 16,196 (213)
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Structural and functional diversity of cathelicidins.
2017Cathelicidins are a ubiquitous family of host defence peptides (HDPs) in vertebrate animals. Unlike other HDP families, they are defined by the common and relatively well conserved proregion rather than the mature active peptides, which are highly diverse and conform to at least five different structural groups.
TOSSI, ALESSANDRO +3 more
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Sensitivity of Chlamydia suis to cathelicidin peptides
Veterinary Microbiology, 2007Nine Chlamydia suis isolates, obtained from pigs with conjunctivitis, were molecularly characterized by ompA sequencing and their in vitro susceptibility to six cathelicidin peptides (SMAP-29, BAC-7, BMAP-27, BMAP-27, BMAP-28, PG-1, LL-37) determined in cell culture.
DONATI, MANUELA +11 more
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Cathelicidins - Natures Attempt at Combinatorial Chemistry
Combinatorial Chemistry & High Throughput Screening, 2005Cathelicidins are a family of diverse antimicrobial peptides found in granules of mammalian neutrophils. Cathelicidins are active against a broad range of microbes in different environments. Aside from their antimicrobial activity, cathelicidins possess other biological properties including cytotoxic activity towards mammalian cells.
Ole E, Sorensen, Niels, Borregaard
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Roles of cathelicidins in inflammation and bone loss
Odontology, 2014Body surface tissues, such as the oral cavity, contact directly with the external environment and are continuously exposed to microbial insults. Cathelicidins are a family of antimicrobial peptides that are found in mammalian species. Humans and mice have only one cathelicidin. Cathelicidins are expressed in a variety of surface tissues.
Yuko, Nakamichi +3 more
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Expression of cathelicidin in recurrent throat infection
International Journal of Pediatric Otorhinolaryngology, 2006Epithelial cells can be called the first line of a defense barrier to microorganisms by the innate immune system. The antimicrobial peptides are the major participants of this system. Cathelicidins are a family of peptides thought to provide an innate defensive barrier against a variety of potential microbial pathogens.To evaluate the expression of the
Jae-Jun, Song +7 more
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Cathelicidins, multifunctional peptides of the innate immunity
Journal of Leukocyte Biology, 2003AbstractCathelicidins comprise a family of mammalian proteins containing a C-terminal cationic antimicrobial domain that becomes active after being freed from the N-terminal cathelin portion of the holoprotein. Many other members of this family have been identified since the first cathelicidin sequences were reported 10 years ago.
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Cathelicidins: a family of endogenous antimicrobial peptides
Current Opinion in Hematology, 2002The cytoplasmic granules of mammalian neutrophils contain several antimicrobial peptides. Some, like defensins, are fully processed before storage, whereas others are stored as precursors that require additional processing. Cathelicidins are bipartite molecules with an N-terminal cathelin domain and an antimicrobial C-terminal domain. Humans apparently
Robert I, Lehrer, Tomas, Ganz
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International Journal of Systems Biology and Biomedical Technologies, 2013
Cathelicidins constitute important antimicrobial peptides of innate immunity. In order to elucidate the evolutionary history of cathelicidins, the author performed comprehensive phylogenetic analyses of cathelicidin homologs in all available genomes including those completed recently. The organization of cathelicidin genes, as well as the secondary and
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Cathelicidins constitute important antimicrobial peptides of innate immunity. In order to elucidate the evolutionary history of cathelicidins, the author performed comprehensive phylogenetic analyses of cathelicidin homologs in all available genomes including those completed recently. The organization of cathelicidin genes, as well as the secondary and
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Cathelicidins and functional analogues as antisepsis molecules
Expert Opinion on Therapeutic Targets, 2007The emergence of antibiotic-resistant bacteria together with the limited success of sepsis therapeutics has lead to an urgent need for the development of alternative strategies for the treatment of systemic inflammatory response syndrome and related disorders.
Mookherjee N. +2 more
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Cathelicidins - a family of multifunctional antimicrobial peptides
Cellular and Molecular Life Sciences (CMLS), 2003One component of host defence at mucosal surfaces are epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in several mammalian species.
R, Bals, J M, Wilson
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