Results 171 to 180 of about 102,568 (340)

Integrated ‘Shield‐Spear’ Biological Patch for Fibrosis‐Free Bladder Reconstruction

open access: yesAdvanced Science, EarlyView.
Fibrosis‐free bladder reconstruction remains challenging. This study pioneers an integrated “shield‐spear” patch: The outer anionic hydrogel layer captures GATA6+ macrophages to suppress collagen overexpression, while the inner S100 aptamer‐engineered EVs target Schwann cells to downregulate the TGFβ/Smad pathway—inhibiting fibrosis with enhanced wound
Xiaoqi Wu   +14 more
wiley   +1 more source

Lysosomal Cathepsin S Escape Facilitates Near Infrared Light‐Triggered Pyroptosis Via an Antibody‐Indocyanine Green Conjugate

open access: yesAdvanced Science, EarlyView.
ICAM1 antibody‐bound ICG triggers tumor‐specific, caspase‐1‐independent pyroptosis via CTSS‐mediated GSDMD cleavage, activates antitumor immunity, and synergizes with anti–PD‐1 therapy, offering a non‐apoptotic strategy to overcome resistance in cancer treatment.
Fan Chen   +17 more
wiley   +1 more source

Electrophysiological findings and long-term follow-up of patients with the permanent form of junctional reciprocating tachycardia treated by catheter ablation.

open access: bronze, 1992
Walter W. Chien   +6 more
openalex   +1 more source

Viral‐Directed Augmentation of Kupffer Cell Cross‐Presentation Provokes Antitumor Immunity Against Liver Metastasis

open access: yesAdvanced Science, EarlyView.
Targeting Kupffer cells (KC) with a single intravenous infusion of the oncolytic virus VSV‐M51R rather than VSV‐WT induces effective tumor regression in various types of liver metastatic cancers in mice. VSV‐M51R promotes KC proliferation and enhances their antigen cross‐presentation capacity without compromising viability, leading to the induction of ...
Chen Chen   +8 more
wiley   +1 more source

Effects of Propofol or Isoflurane Anesthesia on Cardiac Conduction in Children Undergoing Radiofrequency Catheter Ablation for Tachydysrhythmias [PDF]

open access: bronze, 1995
J. P. Lavoie   +5 more
openalex   +1 more source

Noninvasive cardiac radiation for ablation of ventricular tachycardia [PDF]

open access: yes, 2017
Cooper, Daniel   +12 more
core   +2 more sources

Nanoparticle Drug Delivery Systems for Atherosclerosis: Precision Targeting, Inflammatory Modulation, and Plaque Stabilization

open access: yesAdvanced Science, EarlyView.
This review first summarizes the complex pathogenesis of atherosclerosis and outlines the limitations of conventional therapies. It then explores innovative nanoparticle drug delivery system (NDDS) developments, detailing their precision targeting strategies, responsiveness to plaque‐specific stimuli, modulation of key pathological processes, and ...
Yunqi Zhang   +13 more
wiley   +1 more source

Genetic Manipulation of Mammalian Cells in Microphysiological Hydrogels

open access: yesAdvanced Science, EarlyView.
Supply channels for cells embedded in gels can be used for in situ genetic manipulation. Abstract Engineering functional 3D tissue constructs is essential for developing advanced organ‐like systems, with applications ranging from fundamental biological research to drug testing. The generation of complex multicellular structures requires the integration
Anna C. Jäkel   +2 more
wiley   +1 more source

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