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Divalent Cations, Nucleotides, and Actin Structure
2001Actin has one high-affinity site for a divalent cation, with a Kd for Ca2+ and Mg2+ in the nanomolar range. This binding site is located at the bottom of the cleft between the two domains of the molecule (Fig. 1). The cation is coordinated not only by amino acid residues but also by the oxygen of the γ- and/or β- phosphate groups of the nucleotide, ADP
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Potentiation of Acetylcholine Receptors by Divalent Cations
Molecular Pharmacology, 2006Divalent cations promote activation of several nicotinic acetylcholine receptor (AChR) subtypes, presumably by lowering the energetic barrier between open and closed conformations. In wild-type alpha7 AChRs, binding of calcium to a particular part of the extracellular domain is required for potentiating activation. McLaughlin et al. (p.
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Divalent Cations in Essential Hypertension
New England Journal of Medicine, 1984openaire +2 more sources
The role of divalent cations in epidermolysis.
The British journal of dermatology, 1976In experiments designed to elucidate the role of divalent cations in maintaining the integrity of the epidermis, newborn mouse skin was incubated in ethylenediamine tetraacetic acid (EDTA) or ethylene glycol tetraacetic acid (EGTA). In EDTA, epidermolysis occurred and was confirmed by rubbing the specimen to demonstrate that a sheet of epidermis could ...
R L, Dimond, K L, Erickson, K D, Wuepper
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Effects of three divalent cations
2003Our aim was to compare the effects of the divalent cations, namely magnesium, zinc, and manganese on the arterial blood pressures and heart rate of guinea pigs. Eighteen guinea pigs weighing 500-700 g were divided into three groups (six in each group), and three divalent cations as sulfate salt (MgSO4, ZnSO4, MnSO4) were administered to all animals ...
Onat, N, Süzer, Ö
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Intraluminal bioavailability of divalent cations
Current Opinion in Gastroenterology, 2013openaire +2 more sources
The luminescent properties of divalent europium complexes of crown ethers and cryptands
Coordination Chemistry Reviews, 1998Jianzhuang Jiang +2 more
exaly
Photochemical Manipulation Of Divalent Cation Levels
Annual Review of Physiology, 1990openaire +2 more sources