Divalent Cation Signaling in Clostridium perfringens Spore Germination [PDF]
Microorganisms, 2023 Spore germination plays an essential role in the pathogenesis of Clostridium perfringens-associated food poisoning. Germination is initiated when bacterial spores sense various stimuli, including chemicals and enzymes.
Roua Almatrafi +2 more
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Role of Divalent Cations in HIV-1 Replication and Pathogenicity
Viruses, 2020 Divalent cations are essential for life and are fundamentally important coordinators of cellular metabolism, cell growth, host-pathogen interactions, and cell death.
Nabab Khan +2 more
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The structural basis of divalent cation block in a tetrameric prokaryotic sodium channel [PDF]
Nature Communications, 2023 Divalent cation block is observed in various tetrameric ion channels. For blocking, a divalent cation is thought to bind in the ion pathway of the channel, but such block has not yet been directly observed.
Katsumasa Irie +4 more
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CNNM proteins selectively bind to the TRPM7 channel to stimulate divalent cation entry into cells. [PDF]
PLoS Biology, 2021 Magnesium is essential for cellular life, but how it is homeostatically controlled still remains poorly understood. Here, we report that members of CNNM family, which have been controversially implicated in both cellular Mg2+ influx and efflux ...
Zhiyong Bai +11 more
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Structural insights into regulation of CNNM-TRPM7 divalent cation uptake by the small GTPase ARL15 [PDF]
eLife, 2023 Cystathionine-β-synthase (CBS)-pair domain divalent metal cation transport mediators (CNNMs) are an evolutionarily conserved family of magnesium transporters.
Luba Mahbub +11 more
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Enhancing the Dye-Rejection Efficiencies and Stability of Graphene Oxide-Based Nanofiltration Membranes via Divalent Cation Intercalation and Mild Reduction [PDF]
Membranes, 2022 Laminar graphene oxide (GO) membranes have demonstrated great potential as next-generation water-treatment membranes because of their outstanding performance and physicochemical properties. However, solute rejection and stability deterioration in aqueous
Hobin Jee +6 more
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Insights into divalent cation regulation and G13-coupling of orphan receptor GPR35 [PDF]
Cell Discovery, 2022 Endogenous ions play important roles in the function and pharmacology of G protein-coupled receptors (GPCRs) with limited atomic evidence. In addition, compared with G protein subtypes Gs, Gi/o, and Gq/11, insufficient structural evidence is accessible ...
Jia Duan +12 more
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Divalent cation and chloride ion sites of chicken acid sensing ion channel 1a elucidated by x-ray crystallography. [PDF]
PLoS ONE, 2018 Acid sensing ion channels (ASICs) are proton-gated ion channels that are members of the degenerin/epithelial sodium channel superfamily and are expressed throughout central and peripheral nervous systems.
Nate Yoder, Eric Gouaux
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Divalent cation signaling in immune cells. [PDF]
Trends Immunol, 2014 Divalent cations of two alkaline earth metals Ca(2+) and Mg(2+) and the transition metal Zn(2+) play vital roles in the immune system, and several immune disorders are associated with disturbances of their function. Until recently only Ca(2+) was considered to serve as a second messenger.
Chaigne-Delalande B, Lenardo MJ.
europepmc +4 more sources
Membranes, 2023 Positively charged nanofiltration (NF) technology is considered a green and low-cost method for mono/divalent cation separation. Nevertheless, the separation rejection mechanisms of these NF membranes have yet to be extensively investigated. In this work,
Enlin Wang +6 more
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