Fluorescent Protein-Based Ca2+ Sensor Reveals Global, Divalent Cation-Dependent Conformational Changes in Cardiac Troponin C. [PDF]
Cardiac troponin C (cTnC) is a key effector in cardiac muscle excitation-contraction coupling as the Ca2+ sensing subunit responsible for controlling contraction. In this study, we generated several FRET sensors for divalent cations based on cTnC flanked
Myriam A Badr +3 more
doaj +2 more sources
Structural Insights into Divalent Cation Modulations of ATP-Gated P2X Receptor Channels [PDF]
P2X receptors are trimeric ATP-gated cation channels involved in physiological processes ranging widely from neurotransmission to pain and taste signal transduction. The modulation of the channel gating, including that by divalent cations, contributes to
Go Kasuya +7 more
doaj +2 more sources
Divalent Cation Modulation of Ion Permeation in TMEM16 Proteins. [PDF]
Intracellular divalent cations control the molecular function of transmembrane protein 16 (TMEM16) family members. Both anion channels (such as TMEM16A) and phospholipid scramblases (such as TMEM16F) in this family are activated by intracellular Ca2+ in ...
Nguyen DM, Kwon HC, Chen TY.
europepmc +2 more sources
Overcoming divalent cation sensitivity is not the only challenge for functional study of ABC transporters within polymer lipid particles. [PDF]
Proteins of the ATP-binding cassette (ABC) transporter superfamily are involved in diverse biological processes including multidrug resistance. As membrane proteins, they exist within a complex lipid environment, and often it is necessary to isolate them
Hawkins OP +5 more
europepmc +2 more sources
Divalent Cation Removal by Donnan Dialysis for Improved Reverse Electrodialysis. [PDF]
Divalent cations in feedwater can cause significant decreases in efficiencies for membrane processes, such as reverse electrodialysis (RED). In RED, power is harvested from the mixing of river and seawater, and the obtainable voltage is reduced and the ...
Rijnaarts T +4 more
europepmc +2 more sources
Wafer-enhanced electrodeionization (WE-EDI) is an electrically driven separations technology that occurs under the influence of an applied electric field and heavily depends on ion exchange resin chemistry. Unlike filtration processes, WE-EDI can be used
Humeyra B. Ulusoy Erol +2 more
doaj +1 more source
Activation of Deoxyribonucleases by Divalent Cations [PDF]
The activation of DNase I by Mg, Mn, Co, Ni, Fe, Cd, Zn, Ba, Sr, Ca, and Cu ions has been studied by several methods, at different pH and salt concentrations. Mg, Mn, and Co are the best activators for initial stages of degradation. A synergistic effect is shown only by the pair Mg-Ca. Optimal pH of action is always situated at 6.5.
V, DESREUX, R, HACHA, E, FREDERICQ
openaire +2 more sources
Adsorption of Divalent Cations on DNA [PDF]
The distribution of divalent ions in semidilute solutions of high-molecular-mass DNA containing both sodium chloride and strontium chloride in near-physiological conditions is studied by small-angle x-ray scattering and by small-angle neutron scattering.
Morfin, Isabelle +6 more
openaire +3 more sources
Cation diffusion facilitators transport initiation and regulation is mediated by cation induced conformational changes of the cytoplasmic domain. [PDF]
Cation diffusion facilitators (CDF) are part of a highly conserved protein family that maintains cellular divalent cation homeostasis in all domains of life.
Natalie Zeytuni +13 more
doaj +1 more source
Aggregation of Nucleosomes by Divalent Cations [PDF]
Conditions of precipitation of nucleosome core particles (NCP) by divalent cations (Ca(2+) and Mg(2+)) have been explored over a large range of nucleosome and cation concentrations. Precipitation of NCP occurs for a threshold of divalent cation concentration, and redissolution is observed for further addition of salt. The phase diagram looks similar to
de Frutos, Marta +3 more
openaire +2 more sources

