Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Discrete typing units of Trypanosoma cruzi identified in rural dogs and cats in the humid Argentinean Chaco [PDF]
, 2012 The discrete typing units (DTUs) of Trypanosoma cruzi that infect domestic dogs and cats have rarely been studied. With this purpose we conducted a cross-sectional xenodiagnostic survey of dog and cat populations residing in 2 infested rural villages in ...
Cardinal, Marta Victoria +5 more
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Heart failure is common in diabetic cats : findings from a retrospective case-controlled study in first-opinionpractice [PDF]
, 2007 Diabetes mellitus is common in the cat and the prevalence of this condition appears to be increasing (Peterson 1998,Rand and Marshall 2004, Rand and others 2004). The prognosis for cats with diabetes mellitus in first opinion practice has received little
Blue Skies Research Grant - RCVS Trust (Funder) +2 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Pasireotide for the Medical Management of Feline Hypersomatotropism [PDF]
, 2015 BACKGROUND: Feline hypersomatotropism (HST) is a cause of diabetes mellitus in cats. Pasireotide is a novel multireceptor ligand somatostatin analog that improves biochemical control of humans with HST.
Abraham +45 more
core +2 more sources
More than one way to improve a CAT: Outcomes and reflections on two iterations of the Queen Square Intensive Comprehensive Aphasia Programme [PDF]
, 2023 Alexander Leff +7 more
openalex +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Vitamin E requirements of adult domestic cats (Felis catus) fed diets containing high levels of fish oil : a thesis presented in partial fulfilment of the requirement for the degree of Master of Nutritional Sciences at Massey University, Palmerston North, New Zealand [PDF]
, 1999 The vitamin E (α-tocopherol) requirement of adult cats fed diets containing high levels of fish oil was investigated. Thirty-two (16 male, 16 female) adult domestic cats (Felis catus) were randomly allocated to four groups according to sex and fed one of
Wu, Yuben
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