Results 31 to 40 of about 193,286 (265)

2070 High-intensity focused ultrasound (HIFU) can be used synergistically with tamoxifen to overcome resistance in preclinical and patient derived xenograft models

open access: yesJournal of Clinical and Translational Science, 2018
OBJECTIVES/SPECIFIC AIMS: The goal of this study is to evaluate a potential strategy to overcome tamoxifen (tam) resistance by using tam in combination with high-intensity focused ultrasound (HIFU).
Rachel Sabol   +4 more
doaj   +1 more source

Risk factors associated with cat parasites in a feline medical center

open access: yesJournal of Feline Medicine and Surgery Open Reports, 2021
Objectives The present study was carried out to evaluate the risk factors for and presence of intestinal parasites in cats at the feline hospital ‘CEME Gatos’, Mexico City.
Tamara Libertad Iturbe Cossío   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The Best Model for a Cat is the Same Cat … or is It? [PDF]

open access: yesEpilepsy Currents, 2007
Effect of Antiepileptic Drugs on Spontaneous Seizures in Epileptic Rats. Nissinen J, Pitkänen A. Epilepsy Res 2007;73:181–191. The present study investigated whether spontaneously seizing animals are a valid model for evaluating antiepileptic compounds in the treatment of human epilepsy.
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Natives Against Invaders: Shared Use of Space and Temporal Segregation of Clouded Tiger‐Cats (Leopardus pardinoides) and Domestic Dogs (Canis familiaris) in an Isolated Protected Area

open access: yesEcology and Evolution
Domestic dogs are widely distributed and exert profound effects on ecosystems, through competition, disease transmission, and killing of native species.
J. C. Cepeda‐Duque   +6 more
doaj   +1 more source

Part 2: A Sector-Wide Survey of UK/British Isles Shelter Organisations Caring for Cats: Caregiver-Reported Approaches to Assessments, Behaviour Management and Homing Decisions

open access: yesVeterinary Sciences
Shelter organisations take responsibility for the care, assessment and homing of large numbers of domestic cats from diverse backgrounds. However, not all cats that come under shelter care are suited to close human-cohabitation or to certain types of ...
Lauren R. Finka   +6 more
doaj   +1 more source

Acquired esophageal stricture in the dog: a case report

open access: yesVeterinární Medicína, 2004
Complicated case, which after several surgical interventions ended up with an acquired esophageal stricture is presented. The possibility of reflux esophagitis should be kept in mind during postoperative period, especially in primarily troubled patients.
M. Vlasin   +3 more
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Part 1: A Sector-Wide Survey of UK/British Isles Shelter Organisations Caring for Cats: Caregiver-Reported Approaches to Housing, Husbandry and General Care Provision

open access: yesVeterinary Sciences
Meeting the physiological and psychological needs of shelter cats through appropriate care is critical to reducing stress and disease risk, as well as enabling positive homing outcomes. Shelter organisations across the British Isles provide care for many
Lauren R. Finka   +6 more
doaj   +1 more source

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