Results 31 to 40 of about 257,706 (312)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Best Model for a Cat is the Same Cat … or is It? [PDF]
Epilepsy Currents, 2007 Effect of Antiepileptic Drugs on Spontaneous Seizures in Epileptic Rats. Nissinen J, Pitkänen A. Epilepsy Res 2007;73:181–191. The present study investigated whether spontaneously seizing animals are a valid model for evaluating antiepileptic compounds in the treatment of human epilepsy.
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Serum symmetric dimethylarginine concentration in healthy horses and horses with acute kidney injury
BMC Veterinary Research, 2020 Background There are limited options to diagnose acute kidney injury (AKI) in horses. Symmetric dimethylarginine (SDMA) is routinely used in human and small animal medicine.
Natalia Siwinska +4 more
doaj +1 more source
, 2007 Diabetes mellitus is common in the cat and the prevalence of this condition appears to be increasing (Peterson 1998,Rand and Marshall 2004, Rand and others 2004). The prognosis for cats with diabetes mellitus in first opinion practice has received little
Little, C.J.L. +3 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Scientific ReportsRecently, the tiger-cat species complex was split into Leopardus tigrinus and Leopardus guttulus, along with other proposed schemes. We performed a detailed analysis integrating ecological modeling, biogeography, and phenotype of the four originally ...
Tadeu G. de Oliveira +41 more
doaj +1 more source
Simulating two-sided mobility platforms with MaaSSim.
PLoS ONE, 2022 Two-sided mobility platforms, such as Uber and Lyft, widely emerged in the urban mobility landscape. Distributed supply of individual drivers, matched with travellers via intermediate platform yields a new class of phenomena not present in urban mobility
Rafał Kucharski, Oded Cats
doaj +1 more source
Urinary felinine excretion in intact male cats is increased by dietary cystine
, 2008 Felinine is a branched-chain sulfur amino acid present in the urine of certain Felidae, including domestic cats. The objective of the present study was to determine if additional cystine and/or dietary N would increase felinine and N-acetylfelinine ...
Rogers, Q.R. +4 more
core +1 more source