Results 51 to 60 of about 193,286 (265)
Simulating two-sided mobility platforms with MaaSSim.
PLoS ONE, 2022 Two-sided mobility platforms, such as Uber and Lyft, widely emerged in the urban mobility landscape. Distributed supply of individual drivers, matched with travellers via intermediate platform yields a new class of phenomena not present in urban mobility
Rafał Kucharski, Oded Cats
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
A framework to refocus the conversation around the welfare of UK purebred cats
Animal WelfarePreviously, consideration of purebred cat welfare has focused heavily on links between specific breeds and their predispositions to disease, extreme morphology, and behavioural traits.
Claire Roberts +3 more
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FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
AnimalsFree-living unowned cats are prevalent across the UK and may experience numerous welfare challenges. However, there is limited research around this. Cat shelter workers were interviewed on the complexities of unowned cat welfare and management, current ...
Avni Bhatia +4 more
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Journal of Clinical and Translational Science, 2020 OBJECTIVES/GOALS: This study has two primary aims: 1) evaluate points of success and failure in connecting hepatitis C virus (HCV) positive homeless patients to care following a preliminary positive rapid HCV test result, and 2) describe the barriers ...
Riley Eli Santiago, Janna Wisniewski
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Physiological Values of P-Wave Dispersion in Silesian Breed Horses and Polish Primitive Horses
Journal of Veterinary Research, 2013 Electrocardiographic examinations were performed on 45 Silesian breed horses (group K, 3-16-year-old, 16 stallions, 29 mares) and on 25 Polish Primitive breed horses (group P, 1.5-19-year-old, two stallions, six geldings, 17 mares).
Michlik Katarzyna +4 more
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BMC Veterinary Research, 2018 Background Capsaicin and dihydrocapsaicin are alkaloids with analgesic effects in humans and animals. When used locally, both of them minimalise pain sensation by defunctionalising nerve endings.
A. Zak +6 more
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A modified Sydney system for the diagnosis of chronic gastritis in dogs
Acta Veterinaria Scandinavica, 2020 Background The Sydney system for assessing inflammatory lesions in the gastric mucosa is based on endoscopic and histological examinations. This study aimed to apply the Sydney system to diagnose gastritis in dogs.
Jolanta Spużak +4 more
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