Results 51 to 60 of about 605,224 (307)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A framework to refocus the conversation around the welfare of UK purebred cats

Animal Welfare
Previously, consideration of purebred cat welfare has focused heavily on links between specific breeds and their predispositions to disease, extreme morphology, and behavioural traits.
Claire Roberts, Rae Foreman-Worsley, Dan G. O’Neill, Jennifer L. McDonald   +3 more
doaj   +1 more source

Physiological Values of P-Wave Dispersion in Silesian Breed Horses and Polish Primitive Horses

Journal of Veterinary Research, 2013
Electrocardiographic examinations were performed on 45 Silesian breed horses (group K, 3-16-year-old, 16 stallions, 29 mares) and on 25 Polish Primitive breed horses (group P, 1.5-19-year-old, two stallions, six geldings, 17 mares).
Michlik Katarzyna, Noszczyk-Nowak Agnieszka, Pasławska Urszula, Janus Izabela, Nicpoń Józef   +4 more
doaj   +1 more source

The detection of capsaicin and dihydrocapsaicin in horse serum following long-term local administration

BMC Veterinary Research, 2018
Background Capsaicin and dihydrocapsaicin are alkaloids with analgesic effects in humans and animals. When used locally, both of them minimalise pain sensation by defunctionalising nerve endings.
A. Zak, N. Siwinska, M. Slowikowska, H. Borowicz, P. Szpot, M. Zawadzki, A. Niedzwiedz   +6 more
doaj   +1 more source

A modified Sydney system for the diagnosis of chronic gastritis in dogs

Acta Veterinaria Scandinavica, 2020
Background The Sydney system for assessing inflammatory lesions in the gastric mucosa is based on endoscopic and histological examinations. This study aimed to apply the Sydney system to diagnose gastritis in dogs.
Jolanta Spużak, Marcin Jankowski, Krzysztof Kubiak, Kamila Glińska-Suchocka, Rafał Ciaputa   +4 more
doaj   +1 more source

The nucleoside analog GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies. [PDF]

, 2018
Feline infectious peritonitis (FIP) is a common and highly lethal coronavirus disease of domestic cats. Recent studies of diseases caused by several RNA viruses in people and other species indicate that antiviral therapy may be effective against FIP in ...
Bauer, K, Eckstrand, C, Liepnieks, M, Murakami, E, Murphy, BG, Park, Y, Pedersen, NC, Perron, M   +7 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Evaluation of renal perfusion in hyperthyroid cats before and after radioiodine treatment [PDF]

, 2017
Background: Hyperthyroidism and chronic kidney disease (CKD) are common in elderly cats. Consequently, both diseases often occur concurrently. Furthermore, renal function is affected by thyroid status. Because changes in renal perfusion play an important
Adams, Adams, Becker, Boag, Brown, Daniel, Debruyn, Dong, Dong, Fischer, Gauthier, Graves, Grenier, Haers, Herget-Rosenthal, Hoek, Hoek, Hyvelin, Kay, Ma, Milner, Ohlerth, Paepe, Paepe, Peterson, Riensche, Slater, Stock, Stock, Stock, Tang, Tsuruoka, Vaske, Volckaert, Williams   +34 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Detecting acute kidney injury in horses by measuring the concentration of symmetric dimethylarginine in serum

Acta Veterinaria Scandinavica, 2021
Background Acute kidney injury (AKI) in horses may develop as a complication of a primary disease or following the administration of nephrotoxic drugs, and may pose a diagnostic challenge.
Natalia Siwinska, Agnieszka Zak, Urszula Paslawska   +2 more
doaj   +1 more source