Results 31 to 40 of about 264,785 (288)
El problema de Dios no ha sido considerado de una manera unívoca a través del tiempo. En esta reflexión no sólo han variado las respuestas, sino también los planteos del problema, cuyo objeto –Dios– es en sí mismo problemático, ya que no es objeto de ...
Dulce María Santiago
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape for various malignancies, but they are associated with a range of immunerelated adverse events, including rare hematological complications.
Adolfo Fernández-Sánchez +6 more
doaj +1 more source
¿Causa eficiente o causa final?
La atención siempre creciente por parte de la crítica y, en particular, de estudiosos que a nivel internacional se ocupan de la obra metafísica del teólogo granadino Francisco Suárez, ha hecho que se profundicen diversas temáticas contenidas en ella. Esto se debe, en especial, por la importante función que esa ha tenido, y todavía tiene, de mantener ...
openaire +2 more sources
El estrés tiene un efecto negativo en la función inmune y en la respuesta inmune en pacientes con enfermedad autoinmune, infecciosa y cáncer. Los estudios realizados por los autores latinoamericanos, publicados en las bases de datos Scielo y Latindex ...
Felipe Da Silva Santos +1 more
semanticscholar +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Validación de la causa básica de defunción en las muertes que requieren intervención medicolegal
Background: Deaths due to external causes require additional medical tests in order to determine the cause of death. If these results are not incorporated into the death register these causes may be misclassified.
Mercè Gotsens +9 more
semanticscholar +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Immunoparesis or suppression of polyclonal immunoglobulins is a very common condition in newly diagnosed myeloma patients. However, the recovery of polyclonal immunoglobulins in the setting of immune reconstitution after autologous stem cell ...
Verónica González-Calle +18 more
doaj +1 more source
Prijenos vlasništva fiduciae causa i causa donationis
U radu se obrađuje problem obuhvata i značenja prijenosa (fidi) fiduciae causa s obzirom na tekstove prema kojima je došlo do fiducijarnog prijenosa vlasništva s uključenom, kao međufazom ili konačnom fazom, svrhom darovanja. Analizirani su fragmenti iz Digesta za koje se u romanistici smatra da su se izvorno odnosili na fiduciju.
openaire +2 more sources

