Results 31 to 40 of about 23,465 (251)

How Organisms Gained Causal Independence and How It Might Be Quantified

open access: yesBiology, 2018
Two broad features are jointly necessary for autonomous agency: organisational closure and the embodiment of an objective-function providing a ‘goal’: so far only organisms demonstrate both.
Keith Douglas Farnsworth
doaj   +1 more source

No Good Arguments for Causal Closure [PDF]

open access: yesMetaphysica, 2020
AbstractMany common arguments for physicalism begin with the principle that the cosmos is “causally closed.” But how good are the arguments for causal closure itself? I argue that the deductive, a priori arguments on behalf of causal closure tend to beg the question. The extant inductive arguments fare no better.
openaire   +1 more source

Explaining causal closure

open access: yesPhilosophical Studies, 2014
The physical realm is causally closed, according to physicalists like me. But why is it causally closed, what metaphysically explains causal closure? I argue that reductive physicalists are committed to one explanation of causal closure to the exclusion of any independent explanation, and that as a result, they must give up on using a causal argument ...
openaire   +2 more sources

Grounding Causal Closure

open access: yesPacific Philosophical Quarterly, 2015
AbstractWhat does it mean to say that mind‐body dualism is causally problematic in a way that other mind‐body theories, such as the psychophysical type identity theory, are not? After considering and rejecting various proposals, I advance my own, which focuses on what grounds the causal closure of the physical realm.
openaire   +2 more sources

The Correlation Between Migraine and Patent Foramen Ovale

open access: yesFrontiers in Neurology, 2020
Background: Migraine is a widespread neurological disorder. The patent foramen ovale (PFO) is a remnant of the fetal circulation. Multiple studies suggest that migraine is more prevalent in subjects with PFO and vice versa.
Kaiming Liu   +5 more
doaj   +1 more source

Influence of the Production Process on the Binding Mechanism of Clinched Aluminum Steel Mixed Compounds

open access: yesJournal of Manufacturing and Materials Processing, 2021
The multi-material design and the adaptability of a modern process chain require joining connections with specifically adjustable mechanical, thermal, chemical, or electrical properties.
Jan Kalich, Uwe Füssel
doaj   +1 more source

Unheard and Under‐Supported: Health‐Related Quality of Life in Children, Adolescents, and Young Adults With Sickle Cell Disease

open access: yesPediatric Blood &Cancer, EarlyView.
Abstract Background Sickle cell disease (SCD) is an autosomal recessive hemoglobinopathy affecting millions of individuals worldwide. The clinical expression and psychosocial burden of SCD vary widely across geographical, cultural, and healthcare system contexts, underscoring the need for setting‐specific approaches to assessment.
Desiré Fantasia   +7 more
wiley   +1 more source

The modulation of stomatal conductance and photosynthetic parameters is involved in Fusarium head blight resistance in wheat.

open access: yesPLoS ONE, 2020
Fusarium head blight (FHB) is one of the most devastating fungal diseases affecting grain crops and Fusarium graminearum is the most aggressive causal species. Several evidences shown that stomatal closure is involved in the first line of defence against
Sara Francesconi   +1 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano   +7 more
wiley   +1 more source

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