Results 191 to 200 of about 1,819,138 (329)

Dynamic Causal Discovery

open access: yes, 2016
Discovering rich causal models computationally can be key to creating human like artificial intelligence. Recent research has detached the notion of time from approaches to causal inference and has thus obscured modelling of and inference over dynamic ...
Schaechtle, Ulrich
core  

Efficient and Trustworthy Causal Discovery

open access: yes
Inferring cause–effect relationships from observational data is a central goal of causality research, as it enables formal reasoning about interventions when experiments are expensive, unethical, or impossible.
MONTAGNA, FRANCESCO
core   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, Volume 20, Issue 7, Page 1663-1666, July 2026.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Causal discovery in manufacturing

open access: yes
Algorithms for causal discovery have recently undergone rapid advances and increasingly draw on flexible nonparametric methods to process complex data. With these advances comes a need for adequate empirical validation of the causal relationships learned
Windisch, Tobias
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, Volume 20, Issue 7, Page 1694-1712, July 2026.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Causal Discovery in Sepsis-A (Random) Walk in the Park? [PDF]

open access: yesJAMA Netw Open
Admon AJ, Carlton EF.
europepmc   +1 more source

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