Results 81 to 90 of about 15,038 (284)

Community food system map (causal loop diagram).

, 2019
A causal loop diagram (CLD) uses arrows to indicate a causal relationship between variables in a system [25]. The CLDs created in this study describe the causal connection between variables that workshop participants deemed to be important, highlighting ...
Boyd Swinburn (675548), Ana Renker-Darby (7251998), Kerry Allan (7252013), Ann E. Bartos (7252016), Wilma E. Waterlander (7252019), Sarah Gerritsen (7251995), Michele Eickstaedt (7252007), Sophia Harré (7252001), Zaynel Sushil (7252010), Debbie A. Raroa (7252004), David Rees (3544232)   +10 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Causal loop diagram of the community response to VAW in Samoa across individual, neighbourhood, extended family and village council domains.

, 2023
Causal loop diagram of the community response to VAW in Samoa across individual, neighbourhood, extended family and village council domains.
Helen Tanielu (16414470), Hattie Lowe (12505193), Louisa Apelu (17241751), Laura Brown (5525264), Jenevieve Mannell (5166668)   +4 more
core   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Applying Community-based System Dynamics to promote child health equity: the case of healthy and fit kids in Milwaukee, WI

Frontiers in Public Health
BackgroundChild health equity is influenced by complex systemic factors, including structural racism, socioeconomic disparities, and access to resources.
Yvonne D. Greer, Yvonne D. Greer, Debra Nevels, Debra Nevels, Amy Meinen, Amy L. Korth, Travis R. Moore, Julia Appel, Kelsey Werner, Larissa Calancie, Andre Lee Ellis, Niky Espy, Shantel Hendricks, Tanya Johnson, Vanessa D. Johnson, Danielle Nabak, Viola Rembert, Christopher Simenz, Nicole Weeks, Angelia Wilks-Tate, Christina D. Economos   +20 more
doaj   +1 more source

Adaptation Behavior of Mango Farmers to Climate Change

Jurnal Manajemen & Agribisnis, 2018
The continuing climate change phenomenon causes disruption to agricultural sector including seasonal fruits such as mangoes. To anticipate the negative effects of climate change, the farmers adapt themselves in order to maintain their mango farming.
Dhany Esperanza, Gilangsari Putri, Elly Rasmikayati, Sara Qanti, Yuyun Yuwariah   +4 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source