Results 101 to 110 of about 1,100,043 (331)

A Cause Analysis Model of Nuclear Accidents in Marine Nuclear Power Plants Based on the Perspective of a Socio-Technical System

Safety
Marine nuclear power plants (MNPPs) represent items of forward-looking high-end engineering equipment combining nuclear power and ocean engineering, with unique advantages and broad application prospects.
Fang Zhao, Ruihua Shu, Shoulong Xu, Shuliang Zou   +3 more
doaj   +1 more source

Kant on causal laws and powers [PDF]

Studies in History and Philosophy of Science Part A, 2014
The aim of the paper is threefold. Its first aim is to defend Eric Watkins's claim that for Kant, a cause is not an event but a causal power: a power that is borne by a substance, and that, when active, brings about its effect, i.e. a change of the states of another substance, by generating a continuous flow of intermediate states of that substance ...
openaire   +3 more sources

The Power of Monitoring Stations and a CO2 Fertilization Effect: Evidence from Causal Relationships between NDVI and Carbon Dioxide [PDF]

, 2008
Robert K. Kaufmann, L. F. Paletta, Hanqin Tian, Ranga B. Myneni, Rosanne D’Arrigo   +4 more
openalex   +1 more source

Causal health impacts of power plant emission controls under modeled and uncertain physical process interference [PDF]

, 2023
Nathan B. Wikle, Corwin Zigler
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

On multi-marker tests for association in case-control studies

Frontiers in Genetics, 2013
Genome-wide association studies (GWAs) have identified thousands of DNA loci associated with a variety of traits. Statistical inference is almost always based on single marker hypothesis tests of association and the respective p-values with Bonferroni ...
Margaret A Taub, Holger R Schwender, Samuel G Younkin, Thomas A Louis, Ingo eRuczinski   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

CPTCFS: CausalPatchTST incorporated causal feature selection model for short-term wind power forecasting of newly built wind farms

International Journal of Electrical Power & Energy Systems
Wind energy is increasingly vital globally, requiring precise output forecasting for stable, efficient power systems. However, this becomes particularly challenging for newly built wind farms that lack historical data.
Hang Zhao, Peidong Xu, Tianlu Gao, Jun Jason Zhang, Jian Xu, David Wenzhong Gao   +5 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source