Results 71 to 80 of about 1,100,043 (331)

Capabilities as causal powers [PDF]

Cambridge Journal of Economics, 2006
The author argues that Sen's capability approach is primarily a philosophical under-labouring exercise aimed at elaborating certain central economic categories, and that the philosophical and methodological underpinnings of Sen's approach are radically different from those of contemporary welfare economics and mainstream economic practice. Sen's notion
openaire   +3 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Network Cosmology

, 2012
Prediction and control of the dynamics of complex networks is a central problem in network science. Structural and dynamical similarities of different real networks suggest that some universal laws might accurately describe the dynamics of these networks,
A Vespignani, A-L Barabási, AG Riess, D Harlow, D Lazer, D Rideout, DB Malament, E Bullmore, EC Zeeman, F Papadopoulos, F Simini, G Korniss, GJ Galloway, J Barrow, J Garriga, L Bombelli, L Bombelli, M Ahmed, M Boguñá, M Boguñá, MEJ Newman, S Boccaletti, S Perlmutter, SW Hawking, T Yamada, V Eguíluz, Y-Y Liu   +26 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Integrating comprehensive functional annotations to boost power and accuracy in gene-based association analysis.

PLoS Genetics, 2020
Gene-based association tests aggregate genotypes across multiple variants for each gene, providing an interpretable gene-level analysis framework for genome-wide association studies (GWAS).
Corbin Quick, Xiaoquan Wen, Gonçalo Abecasis, Michael Boehnke, Hyun Min Kang   +4 more
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

AnchorFCI: harnessing genetic anchors for enhanced causal discovery of cardiometabolic disease pathways

Frontiers in Genetics
IntroductionCardiometabolic diseases, a major global health concern, stem from complex interactions of lifestyle, genetics, and biochemical markers. While extensive research has revealed strong associations between various risk factors and these diseases,
Adèle H. Ribeiro, Milena Crnkovic, Jaqueline Lopes Pereira, Regina Mara Fisberg, Flavia Mori Sarti, Marcelo Macedo Rogero, Dominik Heider, Andressa Cerqueira   +7 more
doaj   +1 more source

Recursive Partitioning for Heterogeneous Causal Effects

, 2015
In this paper we study the problems of estimating heterogeneity in causal effects in experimental or observational studies and conducting inference about the magnitude of the differences in treatment effects across subsets of the population.
Athey, Susan, Imbens, Guido
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

A causal reasoning approach for power transformer failure diagnosis

Frontiers in Energy Research
Extensive research validates the effectiveness of employing Dissolved Gas Analysis (DGA) for diagnosing electric power transformer failures. However, a significant portion of existing research focuses on static data for classifying failure types, lacking
Fei Jiao, Zhenyuan Ma, Qikun Chen, Fengda Zhang, Dezong Zhao   +4 more
doaj   +1 more source