Results 81 to 90 of about 1,021,862 (272)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Intelligent Agents and Causal Inference: Enhancing Decision-Making through Causal Reasoning

open access: yesApplied Sciences
This study examines the incorporation of causal inference methods into intelligent entities and examines the benefits of utilizing causal reasoning to improve decision-making procedures.
Jairo Iván Vélez Bedoya   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Causal Reasoning for Algorithmic Fairness

open access: yesCoRR, 2018
In this work, we argue for the importance of causal reasoning in creating fair algorithms for decision making. We give a review of existing approaches to fairness, describe work in causality necessary for the understanding of causal approaches, argue why causality is necessary for any approach that wishes to be fair, and give a detailed analysis of the
Joshua R. Loftus   +3 more
openaire   +2 more sources

Motivated Causal Reasoning: Partisanship in the US

open access: yes, 2022
This project studies the role of motivated reasoning on causal judgements in the context of partisanship in the ...
Honorata Mazepus, Dimiter Toshkov
core   +1 more source

Dampak strategi membaca digital, dialogis, dan tradisional terhadap keterampilan bahasa, pemahaman cerita, dan penalaran kausal: Studi komparatif

open access: yesDiglosia
The purpose of this study was to investigate the comparative impact of three strategies, namely digital reading, dialogic reading, and traditional reading, on students' receptive and expressive language skills, story comprehension, and causal reasoning ...
Ria Candra Dewi
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Efficient causation on reasoning, discovery and counterfactuals

open access: yesProceedings of the International Florida Artificial Intelligence Research Society Conference
This paper demonstrates a formalism of efficient causation. Efficient causation is one of the four types of basic causations coined by Aristotle.
Xing Xu
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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