Results 71 to 80 of about 39,390 (254)

Extracting Causal Relations in Deep Knowledge Tracing

CoRR
A longstanding goal in computational educational research is to develop explainable knowledge tracing (KT) models. Deep Knowledge Tracing (DKT), which leverages a Recurrent Neural Network (RNN) to predict student knowledge and performance on exercises, has been proposed as a major advancement over traditional KT methods.
Kevin Hong, Kia Karbasi, Gregory J. Pottie   +2 more
openaire   +4 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Multi-Task Sequence Tagging for Denoised Causal Relation Extraction

Mathematics
Extracting causal relations from natural language texts is crucial for uncovering causality, and most existing causal relation extraction models are single-task learning-based models, which can not comprehensively address attributes such as part-of ...
Yijia Zhang, Chaofan Liu, Yuan Zhu, Wanyu Chen   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Green technology innovations, natural gas and resource extraction strategies in BRICS: Modeling impacts on CO2 emission intensity

Sustainable Futures
The article extends beyond conventional models and indicators by initially attempting to capture the complex effects of green technological innovations and changes in natural resource extraction and natural gas production on a novel environmental quality
Shoukat Iqbal Khattak, Anwar Khan, Khadim Hussain   +2 more
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Unmanned Aerial Vehicle Anomaly Detection Based on Causality-Enhanced Graph Neural Networks

Drones
With the widespread application of unmanned aerial vehicles (UAVs), the safety detection system of UAVs has created an urgent need for anomaly detection technology.
Chen Feng, Jun Fan, Zhiliang Liu, Guang Jin, Siya Chen   +4 more
doaj   +1 more source

Informative Causality Extraction from Medical Literature via Dependency-Tree-Based Patterns. [PDF]

J Healthc Inform Res, 2022
Kabir MA, Almulhim A, Luo X, Al Hasan M.
europepmc   +1 more source