Results 31 to 40 of about 345,873 (258)

La argumentación to hoti en Aristóteles

open access: yesTópicos, 2013
The most widespread accounts of the Aristotelian theory of science emphasize enough the importance that Aristotle attributes to demonstration dióti as a way of securing the explanation of facts from their causes; but they frequently underestimate the ...
Jorge Morán y Castellanos
doaj   +1 more source

Las formas como causas en el timeo de platón: las causas inteligentes y su relación con las formas [PDF]

open access: yes, 2007
El objetivo que se persigue con este ensayo es determinar si las Formas que aparecen como principio causal en el Fedón pueden ser identificadas o no con las causas inteligentes del Timeo; ya que puede haber algún otro elemento dentro del diálogo, por ...
Felipe, Carolina
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Destacamento do Revestimento Cerâmico de Fachadas de Edificações em Florianópolis [PDF]

open access: yes, 2014
TCC (graduação) - Universidade Federal de Santa Catarina. Centro Tecnológico. Engenharia Civil.O revestimento cerâmico de fachada é um sistema muito utilizado nos edifícios de Florianópolis, em especial nas regiões próximas do mar.
Souza, Fabio Caon de
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Violência e morte na região metropolitana de Florianópolis, Brasil: tendências da mortalidade por causas externas de 1996 a 2002 [PDF]

open access: yes, 2005
Dissertação ( mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Saúde Publica.Esta dissertação é composta por dois artigos.
D'Agostini, Raquel Alves
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Reflexiones y dudas en torno a los trastornos del espectro autista y su educación.

open access: yesEducatio Siglo XXI, 2012
Desde estas líneas, sin tener la certeza de muchas cosas y dudando de muchas otras, se intenta aportar reflexiones sobre la “eterna novedad” que representa el espectro autista y su educación, conscientes de que la tarea no es fácil.
Paco Jiménez
doaj  

Cinismo organizacional: un análisis holístico de sus orígenes, causas y consecuencias en el ámbito laboral

open access: yesSignos
El cinismo organizacional (co) es una actitud perjudicial que afecta la moral, el desempeño y la estabilidad de las empresas. Se caracteriza por la desconfianza y la negatividad hacia la organización, con causas diversas y efectos que impactan a ...
Pilar Pulido, Carlos Almanza
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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