La argumentación to hoti en Aristóteles
The most widespread accounts of the Aristotelian theory of science emphasize enough the importance that Aristotle attributes to demonstration dióti as a way of securing the explanation of facts from their causes; but they frequently underestimate the ...
Jorge Morán y Castellanos
doaj +1 more source
Las formas como causas en el timeo de platón: las causas inteligentes y su relación con las formas [PDF]
El objetivo que se persigue con este ensayo es determinar si las Formas que aparecen como principio causal en el Fedón pueden ser identificadas o no con las causas inteligentes del Timeo; ya que puede haber algún otro elemento dentro del diálogo, por ...
Felipe, Carolina
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Destacamento do Revestimento Cerâmico de Fachadas de Edificações em Florianópolis [PDF]
TCC (graduação) - Universidade Federal de Santa Catarina. Centro Tecnológico. Engenharia Civil.O revestimento cerâmico de fachada é um sistema muito utilizado nos edifícios de Florianópolis, em especial nas regiões próximas do mar.
Souza, Fabio Caon de
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Violência e morte na região metropolitana de Florianópolis, Brasil: tendências da mortalidade por causas externas de 1996 a 2002 [PDF]
Dissertação ( mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Saúde Publica.Esta dissertação é composta por dois artigos.
D'Agostini, Raquel Alves
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Reflexiones y dudas en torno a los trastornos del espectro autista y su educación.
Desde estas líneas, sin tener la certeza de muchas cosas y dudando de muchas otras, se intenta aportar reflexiones sobre la “eterna novedad” que representa el espectro autista y su educación, conscientes de que la tarea no es fácil.
Paco Jiménez
doaj
El cinismo organizacional (co) es una actitud perjudicial que afecta la moral, el desempeño y la estabilidad de las empresas. Se caracteriza por la desconfianza y la negatividad hacia la organización, con causas diversas y efectos que impactan a ...
Pilar Pulido, Carlos Almanza
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source

