Results 51 to 60 of about 245,793 (265)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Causas célebres y derecho. Estudios iushistóricos sobre la literatura, prensa, opinión pública y proceso judicial [PDF]
, 2012 Estamos ante la segunda edición, ampliada y corregida, del libro CAUSAS CÉLEBRES Y DERECHO, texto integrado por cinco trabajos de destacados iushistoriadores.
Mazzacane, Aldo +4 more
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Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Manifestações patológicas em edificações recentes: causas e consequências [PDF]
, 2020 ArtigoPathological manifestations are a fact that has affected buildings of the most varied types and in the most varied locations, with consequences ranging from an unforeseen expense to a complete interdiction, in this way the present paper seeks to ...
Lopes, Sanderson Aires
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
LA CASA GIBBS Y EL MONOPOLIO SALITRERO PERUANO: 1876-1878
Historia (Santiago), 2008 El objeto de este breve trabajo es mostrar la disposición de Anthony Gibbs & Sons, y de sus filiales, a apoyar el proyecto monopólico salitrero del Perú con recursos monetarios y los manejos de sus directores en la única empresa que, dada su capacidad de
Manuel Ravest Mora
doaj
Causal attribution to cervical cancer
Psicooncologia, 2016 This study aimed to examine the causal attribution for cervical cancer for women with and without the disease. Seventy-eight (78) users from the public healthcare system participated, which were divided into: a clinical group (CG) of women with cervical ...
Ana Carolina Peuker +3 more
doaj +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Causas de la enunciación y posicionamientos subjetivos: Presupuestos teórico-metodológicos del enfoque dialógico de la argumentación y la polifonía [PDF]
, 2023 En este capítulo, presentación del libro Las causas del decir. Aportes del enfoque dialógico de la argumentación y la polifonía al análisis del discurso, se explicitan las bases teóricas y los presupuestos metodológicos que orientan nuestra concepción ...
Garcia Negroni, Maria Marta
core