Results 61 to 70 of about 245,793 (265)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Conflictos, mediación y resolución en la Escuela Infantil

open access: yesRevista de Estudios e Investigación en Psicología y Educación, 2017
La Comunidad Autónoma de Castilla y León emitió hace una década normativa específica sobre la prevención y resolución pacífica de conflictos. Incluye diseño de instrumentos para favorecer la convivencia y la mediación escolar. La indagación presentada se
María Luisa García Rodríguez   +1 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Causas y antecedentes del 15-M. [PDF]

open access: yes
El liberalismo, la socialdemocracia y el comunismo proyectaban los conflictos del presente en el futuro, imaginando la solución, indica el autor. Pero ese esquema ya no funciona en el siglo XXI. El 15M fue la primera expresión de ese presente sin futuro.
Lago, Jorge
core  

El invierno demográfico europeo: causas, consecuencias, propuestas [PDF]

open access: yes, 2012
Europa vive de espaldas al factor demográfico. Al menos eso se deduce de la indiferencia con que muchos países europeos abordan el descenso constante de sus tasas de natalidad.
Contreras, Francisco José
core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Análise de manifestações patológicas em condomínio construído com alvenaria estrutural: estudo de caso [PDF]

open access: yes, 2015
TCC (graduação) - Universidade Federal de Santa Catarina. Centro Tecnológico. Engenharia Civil.O sistema construtivo de alvenaria estrutural é muito utilizado nos dias atuais, sobretudo em edificações de interesse social.
Juliani, Marcela Alejandra
core  

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Destacamento do Revestimento Cerâmico de Fachadas de Edificações em Florianópolis [PDF]

open access: yes, 2014
TCC (graduação) - Universidade Federal de Santa Catarina. Centro Tecnológico. Engenharia Civil.O revestimento cerâmico de fachada é um sistema muito utilizado nos edifícios de Florianópolis, em especial nas regiões próximas do mar.
Souza, Fabio Caon de
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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