Results 101 to 110 of about 172,794 (317)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Downward Causation without Foundations [PDF]
Emergence is interpreted in a non-dualist framework of thought. No metaphysical distinction between the higher and basic levels of organization is supposed, but only a duality of modes of access.
Bitbol, Michel
core
Advances in experimental philosophy of causation
What is the connection between causation and responsibility? Is there a best way to theorize philosophically about causation? Which factors determine and influence what we judge to be the cause of something?
core
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Liang-Kleeman Information Flow: Theory and Applications
Information flow, or information transfer as it may be referred to, is a fundamental notion in general physics which has wide applications in scientific disciplines.
X. San Liang
doaj +1 more source
Causation, Chance and the Rational Significance of Supernatural Evidence [PDF]
Newcomb problems turn on a tension between two principles of choice: roughly, a principle sensitive to the causal features of the relevant situation, and a principle sensitive only to evidential factors.
Huw Price, Price, Huw
core
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
There are a number of phenomena where an apparent animacy requirement exceptionally admits some inanimate causers as felicitous. In this paper I argue that these should be explained not by a syntactically visible animacy feature but rather by a “what-can-
Bridget Copley
doaj +2 more sources
Epistemic states, what an agent knows or beliefs, play a crucial role in people's moral evaluations of the agent's actions. Whether and to what extent epistemic states also influence an agent's perceived causal contribution to an outcome remains the subject of debate.
Kirfel, Lara, Lagnado, David
openaire +1 more source

