Results 141 to 150 of about 172,794 (317)

Causation at different levels : Tracking the commitments of mechanistic explanations

open access: yes, 2011
This paper tracks the commitments of mechanistic explanations focusing on the relation between activities at different levels. It is pointed out that the mechanistic approach is inherently committed to identifying causal connections at higher levels with
Fazekas, Péter
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

The syntax and semantics of laisser in causative constructions

open access: yesIsogloss
The French verb laisser (‘to let’) allows for two different syntactic constructions, an Exceptional Case Marking (ECM) construction and a Faire-Infinitive (FI) construction with a postverbal Causee, and for two different interpretations, authorize and ...
Clémentine Raffy   +2 more
doaj   +1 more source

Mental causation: a defence

open access: yes, 2011
If we accept causal exclusion, property dualism and physical determinism, mental epiphenomenalism follows. Accord-ing to Yablo (1992), we can save mental causation by rejecting causal exclusion and considering the mental/physical relation as an instance ...
Bacchini, Fabio
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Responsibility Regardless of Causation [PDF]

open access: yes, 2014
This paper deals with the relationship between legal responsibility and causation. I argue that legal responsibility is not necessarily rooted in causation. The general claim I aim to disprove is that responsibility is descriptive because it is
Faroldi F, Faroldi, Federico
core  

Three Grades of Downward Causation

open access: yes, 2017
this paper presents three different models of causation that make room in different ways for the idea that there can be downward causation going from the psychological to the physical ...
PAOLINI PAOLETTI, MICHELE   +3 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

On persons, populations, and causal mechanisms. Some critical reflections on Lundh (2023).

open access: yesJournal for Person-Oriented Research
While agreeing with Lundh (2023) on many of his major points, this article also questions the notion of a ‘population psychology.’ It is argued that the knowledge produced in population-level studies, whether correlational, experimental, or mixed, is ...
James T. Lamiell
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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