Results 161 to 170 of about 137,432 (267)

Editorial: New Perspectives to Unlock the Current Impasse in Treating Anorexia Nervosa

Frontiers in Psychology, 2020
Emilio Gutierrez, C. Laird Birmingham
doaj   +1 more source

The Need for a Systems Biology Approach in Cancer Explained. [PDF]

Int J Mol Sci
Zhu H, Zhang X, Nazemalhosseini-Mojarad E, Roelands J, de Muynck LDAN, Ravensbergen CJ, Hoorntje R, Stouten I, Hokland M, Vahrmeijer AL, Tollenaar RAEM, Koster E, Kuppen PJK.   +12 more
europepmc   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

What teleology (if any) does the Organisational Approach naturalise? [PDF]

Hist Philos Life Sci
Cuciniello RR.
europepmc   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

Deconstructing the association of metformin with reduced incidence of seizures and improved seizure control. [PDF]

J Neurol Neurosurg Psychiatry
Kerr WT, McFarlane KN.
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Fibromyalgia and Risk of Alzheimer's DiseaseRelated Dementia: A Nationwide Bidirectional Case-Control Study. [PDF]

Geriatrics (Basel)
Magen E, Magen I, Merzon E, Green I, Golan-Cohen A, Vinker S, Israel A.   +6 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Association of ischaemic stroke/TIA with subsequent oral anticoagulant adherence in patients with atrial fibrillation: a scoping review. [PDF]

BMJ Open
Shukkoor AA, Turgeon RD, De Vera MA, Harrison M, George NE, Loewen PS.   +5 more
europepmc   +1 more source