Results 171 to 180 of about 204,380 (312)

Causation of Cancer [PDF]

American Journal of Public Health and the Nations Health, 1958
openaire   +2 more sources

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Causal Explanation from a Conceptual Engineering Perspective: Non-Reductionism, Precision, and Pluralism. [PDF]

Acta Biotheor
Lee J, Ross LN.
europepmc   +1 more source

Causation and Exposition

SSRN Electronic Journal
Abstract Theoretical accounts of legal causation have traditionally emerged from tort or criminal law scholarship, only occasionally surfacing in commentary on constitutional law. Given their potential to migrate across jurisdictions and influence debates globally, the role of causation is apt to become a distinctive field of inquiry ...
openaire   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Causal attribution in forensic psychological injury: legal causation, validity assessment, and expert reasoning. [PDF]

Front Psychol
Tortes Saint-Jammes J.
europepmc   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Innovation, diffusion and cumulative causation: changes in the Spanish growth regime, 1960-2001 [PDF]

This article presents a model of macroeconomic growth that combines in a single formalization two complementary views on innovation and economic growth, the technology-gap approach and the Kaldorian theory of cumulative causation. The model suggests that
Castellacci, Fulvio
core  

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

The Compatibility of Downward Causation and Emergence

, 2017
In this paper, I shall argue that both emergence and downward causation, which are strongly interconnected, presuppose the presence of levels of reality.
GOZZANO, SIMONE
core