Results 111 to 120 of about 736,528 (287)

Parallel grammaticalizations in Tibeto-Burman : evidence of Sapir's 'Drift' [PDF]

open access: yes, 2010
In chapters seven and eight of his book Language, Sapir talked about what he called ‘drift’, the changes that a language undergoes through time [...]. Dialects of a language are formed when that language is broken into different segments that no longer ...
LaPolla, Randy J.
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Kasi And Bikin Two Causative Strategies In Melayu Tenggara Jauh (Southwest Maluku, Indonesia) [PDF]

open access: yes, 2015
This paper discusses the causative constructions found in Melayu Tenggara Jauh ‘Far Southeast Malay' (MTJ), which is used as lingua franca in Southwest Maluku.
Engelenhoven, A. V. (Aone)
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Systematic Review of Cases of Meningitis in the Absence of Cerebrospinal Fluid Pleocytosis on Lumbar Puncture [PDF]

open access: yes, 2019
Background: Definitive diagnosis of meningitis is made by analysis of cerebrospinal fluid (CSF) culture or polymerase chain reaction (PCR) obtained from a lumbar puncture (LP), which may take days.
Pettigrew, Alexis, Troendle, Michelle
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The role of Persian causative markers in the acquisition of English causative verbs [PDF]

open access: yesJournal of English Language Teaching and Learning, 2012
This project investigates the relationship between lexical semantics and causative morphology in the acquisition of causative/inchoative-related verbs in English as a foreign language by Iranian speakers.
Ali Akbar Jabbari, Mohammad Javad Rezaie
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The semantics of the native greek verb suffixes / Chariton Charitonidis [PDF]

open access: yes, 2011
The aim of this paper is to give the semantic profile of the Greek verb-deriving suffixes -íz(o), -én(o), -év(o), -ón(o), -(i)áz(o), and -ín(o), with a special account of the ending -áo/-ó.
Charitōnidēs, Charitōn Ch.
core  

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