Results 151 to 160 of about 678,027 (356)
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
The causative construction in Lingala
This study of the causative verbal derivation in Lingála, marked by the postradical morpheme -is-, opens with a discussion of irregular causative morphology in some frequently used verbs.
Meeuwis, Michael
core
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
본 연구의 목적은 중국인 한국어 학습자의 한국어 사동과 중국어 사동을 유형별 대응 여부에 따라 한국어 사동 인식과 생산 양상을 실험을 통해 고찰하는 데 있다. 지금까지 중국인 학습자들이 한국어 사동을 인식 양상이나 생산 양상을 분석하는 연구가 많지만 중국인 한국어 학습자의 모국어, 즉 중국어와 유형별로 대응하고 그 유형별로 중국인 한국어 학습자의 한국어 사동을 인식 양상과 생산 양상을 같이 분석한 연구가 없었다. 본 연구는 선행 연구를 바탕으로 한국어
Hua, Shengnan
core
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Cause to celebrate, cause to grumble
AbstractWith a funding tranche of £6.5m; more room available in a planned move out of a 400m2 clean room, into 800m2 in a nearby lab under refurbishment; and the expected delivery in a few months of a £1.12m Thomas Swan MOVPE reactor, the University of Sheffield Engineering & Physical Sciences Research Council's National Centre for III-Vs Technologies ...
openaire +1 more source
Reconsidering Causative Constructions in Ainu
Ainu has a number of causative constructions but only the productive -re/-e/-te (and the indefinite causative -yar/-ar) have been regarded as causative markers so far.
ブガエワ, アンナ
core

