Results 201 to 210 of about 736,528 (287)

Scleral Penetration by a Cryoprobe in Primary Buckling Surgery for Traumatic Retinal Detachment: A Case Report. [PDF]

Case Rep Ophthalmol
Yamada Y, Takesue A, Yokoyama T, Kudo D, Nakao S.   +4 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Drug Reaction with Eosinophilia and Systemic Symptoms in the Electronic Medical Record.

Int Arch Allergy Immunol
Jiang M, Lam L, Kovoor J, Inglis JM, Shakib S, Yuson C, Ali SB, Bacchi S, Kern JS, Sidhu S, Smith W.   +10 more
europepmc   +1 more source

A Case of <i>Corynebacterium diphtheriae</i> Native Mitral and Tricuspid Valve Infective Endocarditis Complicated by Shower Emboli. [PDF]

Case Rep Cardiol
Mashayekan S, Chow T, Gupta J, Huang G.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Exploring the Link Between Causative Agents of Healthcare-Associated Infections and Predisposing Factors Causing Extended Hospital Stays. [PDF]

Cureus
Felifel A, Soltan A, Abolseoud ME, Eltotongy HE, Elnagar F, Ebid M, El Shawadfy F, Eldamaty M, Abouelezz A, Saber E, Afifi M, Ghonaim HHHS, Elashmawy AY, Altayar M, Algharaibeh A, Elsalahi M, Mohamed SHAA, Abousobh ZMM, Sayed A, Eldeib SO, Omar A.   +20 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

A Case of Psoas Abscess Diagnosed With Oral Bacteria as the Causative Pathogen. [PDF]

Cureus
Umemori K, Obata K, Yao M, Fujita K, Ibaragi S.   +4 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Surveillance of central-line-associated blood stream infections (CLABSI) in intensive care units of a tertiary care center in Western India. [PDF]

GMS Hyg Infect Control
Verma P, Gupta S, Bansal S, Pandey GP.
europepmc   +1 more source