Results 241 to 250 of about 678,027 (356)

T Cell Receptor Sharing in Hypersensitivity Pneumonitis. [PDF]

Comput Struct Biotechnol J
Sendama W, Funston W, Davidson RCH, Rostron AJ, Simpson AJ.   +4 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Leishmaniasis in Thailand: A Review of Causative Agents and Situations.

American Journal of Tropical Medicine and Hygiene, 2017
S. Leelayoova, S. Siripattanapipong, J. Manomat, P. Piyaraj, P. Tan-ariya, Lertwut Bualert, M. Mungthin   +6 more
semanticscholar   +1 more source

Assessing future landslide susceptibility and risk escalations under changing LULC and climate conditions in the Western Ghats of Karnataka in India. [PDF]

Sci Rep
Pramanik M, Hegde A.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Cat Bite-Associated Infections of the Upper Extremity Requiring Surgical Treatment: A Report of Two Cases Involving Pasteurella multocida and Capnocytophaga felis. [PDF]

Cureus
Saito K, Hosomi R, Minato T, Kishi H, Matsuura M.   +4 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Profiling causative factors leading to construction project delays in the United Arab Emirates

, 2017
Bekithemba Mpofu, E. Ochieng, C. Moobela, Adri Pretorius   +3 more
semanticscholar   +1 more source

Causal effects of endometriosis on serum 25-hydroxyvitamin D: Evidence from Mendelian randomization study. [PDF]

Medicine (Baltimore)
Jiang H, Tang Y, Huang X, Wang Z, Lin F.
europepmc   +1 more source