Results 111 to 120 of about 4,282,769 (355)
The Professional Medical Journal, 2019 Objectives: The purpose behind this study was to determine the pattern of the causes of death in adult males - a perspective on autopsy. Study Design: Cross sectional study. Period: 2015 to 2016. Setting: Peoples Medical College Hospital, Nawabshah, Shaheed Benazirabad, Sindh, Pakistan.
Mohammad Ismail Salim Memon +2 more
openaire +2 more sources
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Causes of death in patients with extranodal cancer of unknown primary: searching for the primary site [PDF]
, 2014 Matias Riihimäki +3 more
openalex +1 more source
The feeding and breeding ecology of little blue penguins (Eudyptula minor) from Tiritiri Matangi Island, New Zealand : a thesis submitted in partial fulfilment of the requirements for the degree of Master of Science in Conservation Ecology, Massey University [PDF]
, 2006 At present the New Zealand populations of Little Blue Penguins (LBP: Eudyptula minor) are classified as 'Threatened' and in 'Gradual Decline' by the Department of Conservation. Effective conservation management of the North Island sub-species requires an
Geurts, Jacqueline Lee
core
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Reviewing disease burden among rural Indian women [PDF]
, 2004 The disease burden of rural Indian women is reviewed by utilizing the data from the 'Survey of Causes of Death (rural)' annual reports of Registrar General of India supplemented with National family health survey (NFHS-II).
Agnihotram V, Dr. Ramanakumar
core
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
It’s time we made smoking history! Tobacco control in Malta : the present and the future [PDF]
, 1999 Tobacco products have no safe level of consumption. They are the only legal consumer products that cause ill health and premature death when used exactly as the manufacturer intends.
Sammut, Mario R.
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source