Results 111 to 120 of about 2,417,970 (339)
Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim +11 morewiley +1 more sourceCausas múltiples de muerte
Revista Cubana de Higiene y Epidemiología, 1998 Se presenta un estudio de causas múltiples de muerte, en la población cubana de 1 año y más de edad. La información se obtuvo de una muestra de 2 036 defunciones ocurridas durante 4 meses consecutivos en 22 municipios del país.Norma Eneida Ríos Massabot, Ana Consuelo Mesa Machado, Arnaldo Tejeiro Fernández +2 moredoaj The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany +9 morewiley +1 more sourceGlobal, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015
The Lancet, 2016 Haidong Wang, M. Naghavi, Christine Allen, Ryan Barber, Z. Bhutta, A. Carter, Daniel C. Casey, F. Charlson, A. Z. Chen, M. Coates, M. Coggeshall, L. Dandona, D. Dicker, H. Erskine, A. Ferrari, C. Fitzmaurice, Kyle Foreman, M. Forouzanfar, Maya S. Fraser, N. Fullman, P. Gething, Ellen M. Goldberg, Nicholas Graetz, J. Haagsma, Simon Iain Hay, Chantal K Huynh, C. Johnson, N. Kassebaum, Y. Kinfu, X. Kulikoff, Michael Kutz, H. Kyu, H. Larson, J. Leung, Xiaofeng Liang, Stephen S. Lim, M. Lind, R. Lozano, N. Marquez, G. Mensah, Joseph Mikesell, A. Mokdad, M. Mooney, Grant Nguyen, E. Nsoesie, D. Pigott, Christine Pinho, Gregory A. Roth, J. Salomon, Logan Sandar, Naris Silpakit, Amber Sligar, Reed J. D. Sorensen, J. Stanaway, C. Steiner, Stephanie Teeple, Bernadette A. Thomas, C. Troeger, A. VanderZanden, S. Vollset, Valentine Wanga, H. Whiteford, Timothy M Wolock, Leo Zoeckler, K. H. Abate, C. Abbafati, K. Abbas, F. Abd-Allah, S. Abera, D. Abreu, L. Abu-Raddad, G. Abyu, T. Achoki, A. Adelekan, Z. Ademi, A. K. Adou, J. Adsuar, K. Afanvi, A. Afshin, E. Agardh, A. Agarwal, Anurag Agrawal, A. Kiadaliri, O. Ajala, A. Akanda, R. Akinyemi, T. Akinyemiju, N. Akseer, Faris Lami, S. Alabed, Z. Al-Aly, K. Alam, N. Alam, D. Alasfoor, S. Aldhahri, R. Aldridge, M. Alegretti, A. Aleman, Z. A. Alemu, Lily T Alexander, Samia Alhabib, R. Ali, A. Alkerwi, F. Alla, P. Allebeck, Rajaa Al-Raddadi, U. Alsharif, K. Altirkawi, E. A. Martin, N. Alvis-Guzmán, Azmeraw T. Amare, A. Amegah, E. Ameh, H. Amini, W. Ammar, Stephen M. Amrock, H. Andersen, B. Anderson, G. M. Anderson, C. Antonio, A. Aregay, J. Ärnlöv, V. Arsenijevic, A. Artaman, H. Asayesh, R. Asghar, S. Atique, Euripide Avokpaho, A. Awasthi, P. Azzopardi, U. Bacha, A. Badawi, M. Bahit, K. Balakrishnan, A. Banerjee, A. Barać, S. Barker-Collo, T. Bärnighausen, L. Barregard, L. Barrero, Arindam Basu, S. Basu, Y. Bayou, S. Bazargan-Hejazi, J. Beardsley, Neeraj Bedi, E. Beghi, Haileeyesus Adamu Belay, B. Bell, M. Bell, A. Bello, D. Bennett, I. Benseñor, A. Berhane, E. Bernabé, B. Betsu, A. Beyene, N. Bhala, A. Bhalla, S. Biadgilign, B. Bikbov, A. Abdulhak, B. Biroscak, S. Biryukov, E. Bjertness, J. Blore, C. Blosser, M. Bohensky, R. Borschmann, D. Bose, R. Bourne, M. Brainin, C. Brayne, A. Brazinova, N. Breitborde, H. Brenner, J. Brewer, Alexandria Brown, Jonathan C. Brown, T. Brugha, G. Buckle, Z. Butt, Bianca Calabria, Ismael Campos-Nonato, J. Campuzano, J. Carapetis, Rosario Cárdenas, D. Carpenter, J. Carrero, C. Castañeda-Orjuela, Jacqueline Castillo Rivas, F. Catalá-López, F. Cavalleri, Kelly M. Cercy, J. Cerdá, Wanqing Chen, Adrienne Chew, P. Chiang, Mirriam Chibalabala, C. Chibueze, Odgerel Chimed-Ochir, V. Chisumpa, J. Choi, Rajiv Chowdhury, H. Christensen, D. Christopher, Liliana G. Ciobanu, M. Cirillo, A. Cohen, V. Colistro, Mercedes Colomar, Samantha M. Colquhoun, C. Cooper, Leslie T. Cooper, Monica Cortinovis, B. Cowie, J. Crump, James Damsere-Derry, H. Danawi, R. Dandona, Farah Daoud, S. Darby, P. Dargan, J. D. das Neves, G. Davey, A. Davis, D. Davițoiu, E. F. de Castro, Pieter de Jager, D. Leo, L. Degenhardt, R. Dellavalle, Kebede Deribe, A. Deribew, S. Dharmaratne, P. Dhillon, C. Díaz-Torné, E. Ding, Kadine Priscila Bender dos Santos, E. Dossou, T. Driscoll, L. Duan, M. Dubey, B. Duncan, R. Ellenbogen, C. Ellingsen, I. Elyazar, A. Endries, S. Ermakov, B. Eshrati, A. Esteghamati, Kara Estep, Imad D A Faghmous, S. Fahimi, E. J. Faraon, T. Farid, C. Farinha, Andre Faro, M. Farvid, F. Farzadfar, V. Feigin, S. Fereshtehnejad, J. Fernandes, João Fernandes, F. Fischer, J. Fitchett, A. Flaxman, N. Foigt, F. Fowkes, E. França, R. Franklin, Joseph Friedman, J. Frostad, Thomas Fürst, N. Futran, S. Gall, K. Gambashidze, A. Gamkrelidze, P. Ganguly, F. Gankpé, T. Gebre, T. Gebrehiwot, A. Gebremedhin, A. Gebru, J. Geleijnse, B. Gessner, A. Ghoshal, K. Gibney, R. Gillum, S. Gilmour, A. Z. Giref, M. Giroud, Melkamu Dedefo Gishu, G. Giussani, E. Glaser, W. Godwin, H. Gómez-Dantés, P. Gona, A. Goodridge, S. Gopalani, R. Gosselin, C. Gotay, A. Goto, H. Gouda, F. Greaves, H. Gugnani, Rahul Gupta, Rajeev Gupta, Vipin Gupta, R. A. Gutiérrez, N. Hafezi-Nejad, D. Haile, A. Hailu, G. B. Hailu, Y. Halasa, R. Hamadeh, S. Hamidi, Jamie Hancock, A. Handal, G. Hankey, Y. Hao, H. Harb, S. Harikrishnan, J. Haro, Rasmus J Havmoeller, S. Heckbert, I. Heredia-Pi, P. Heydarpour, H. Hilderink, H. Hoek, R. Hogg, M. Horino, N. Horita, H. Hosgood, P. Hotez, D. Hoy, M. Hsairi, A. Htet, M. Htike, G. Hu, Cheng Huang, Hsiang Huang, L. Huiart, A. Husseini, I. Huybrechts, Grace Huynh, K. Iburg, K. Innos, M. Inoue, Veena Iyer, T. Jacobs, K. Jacobsen, N. Jahanmehr, M. Jakovljevic, P. James, Mehdi Javanbakht, S. Jayaraman, A. Jayatilleke, P. Jeemon, P. Jensen, V. Jha, G. Jiang, Ying Jiang, T. Jibat, A. Jiménez-Corona, J. Jonas, T. Joshi, Z. Kabir, R. Kamal, H. Kan, S. Kant, A. Karch, C. Karema, Chante Karimkhani, D. Karletsos, G. Karthikeyan, A. Kasaeian, M. Katibeh, Anil Kaul, N. Kawakami, J. Kayibanda, P. Keiyoro, L. Kemmer, A. Kemp, A. Kengne, A. Keren, M. Kereselidze, C. Kesavachandran, Y. Khader, I. Khalil, Abdur Rahman Khan, E. Khan, Y. Khang, S. Khera, T. Khoja, C. Kieling, Daniel H. Kim, Y. Kim, B. Kissela, N. Kissoon, L. Knibbs, A. Knudsen, Y. Kokubo, D. Kolte, J. Kopec, S. Kosen, P. Koul, A. Koyanagi, N. Krog, B. K. Defo, B. K. Bicer, A. Kudom, E. Kuipers, Veena S. Kulkarni, G. Kumar, G. Kwan, Aparna Lal, D. Lal, R. Lalloo, T. Lallukka, H. Lam, Jennifer O. Lam, S. Langan, V. Lansingh, A. Larsson, D. Laryea, A. Latif, A. Lawrynowicz, J. Leigh, M. Levi, Yongmei Li, M. Lindsay, S. Lipshultz, Patrick Y. Liu, Shiwei Liu, Yang Liu, Loon-Tzian Lo, G. Logroscino, P. Lotufo, R. Lucas, R. Lunevicius, R. Lyons, Stefan Ma, V. Machado, M. Mackay, J. MacLachlan, H. A. E. Razek, M. Magdy, A. Razek, M. Majdan, A. Majeed, R. Malekzadeh, Wondimu Ayele Ayele Manamo, John Mandisarisa, S. Mangalam, C. Mapoma, W. Marcenes, D. Margolis, Gerard R. Martin, J. Martínez-Raga, M. Marzan, F. Masiye, A. Mason-Jones, J. Massano, R. Matzopoulos, B. Mayosi, S. Mcgarvey, J. Mcgrath, M. Mckee, B. McMahon, P. Meaney, A. Mehari, M. Mehndiratta, Fabiola Mejía-Rodríguez, A. Mekonnen, Y. Melaku, P. Memiah, Z. Memish, W. Mendoza, A. Meretoja, T. Meretoja, F. Mhimbira, R. Micha, Anoushka I Millear, T. Miller, M. Mirarefin, Awoke Misganaw, C. Mock, K. Mohammad, A. Mohammadi, S. Mohammed, V. Mohan, G. Mola, L. Monasta, J. M. Hernandez, Pablo Montero, M. Montico, T. Montine, M. Moradi-Lakeh, L. Morawska +499 moresemanticscholar +1 more sourceTherapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim +18 morewiley +1 more sourceGlobal, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
The Lancet, 2015 M. Naghavi, Haidong Wang, R. Lozano, A. Davis, Xiaofeng Liang, Maigeng Zhou, S. Vollset, A. Ozgoren, S. Abdalla, F. Abd-Allah, M. Aziz, S. Abera, V. Aboyans, Biju Abraham, J. Abraham, K. Abuabara, I. Abubakar, L. Abu-Raddad, Niveen M. E. Abu-Rmeileh, T. Achoki, A. Adelekan, Z. Ademi, K. Adofo, A. K. Adou, J. Adsuar, J. Ärnlöv, E. Agardh, D. Akena, M. Khabouri, D. Alasfoor, Mohammed I Albittar, M. Alegretti, A. Aleman, Z. A. Alemu, Rafael Alfonso-Cristancho, Samia Alhabib, Mohammed K. Ali, R. Ali, F. Alla, F. Lami, P. Allebeck, Mohammad A. Almazroa, R. Salman, U. Alsharif, E. Álvarez, Nelson Alviz-Guzman, A. Amankwaa, Azmeraw T. Amare, O. Ameli, Hassan Amini, W. Ammar, H. R. Anderson, B. Anderson, C. Antonio, P. Anwari, Henry Apfel, S. Cunningham, V. Arsenijevic, A. Artaman, Majed Asad, R. Asghar, Reza Assadi, Lydia S. Atkins, C. Atkinson, A. Badawi, M. Bahit, Talal Bakfalouni, K. Balakrishnan, Shivanthi K. Balalla, A. Banerjee, Ryan Barber, S. Barker-Collo, S. Barquera, L. Barregard, L. Barrero, T. Barrientos-Gutiérrez, Arindam Basu, S. Basu, M. Basulaiman, J. Beardsley, Neeraj Bedi, E. Beghi, T. Bekele, M. Bell, C. Benjet, D. Bennett, I. Benseñor, H. Benzian, A. Bertozzi-Villa, T. Beyene, N. Bhala, A. Bhalla, Z. Bhutta, B. Bikbov, A. Abdulhak, S. Biryukov, J. Blore, F. Blyth, M. Bohensky, G. Borges, D. Bose, S. Boufous, R. Bourne, Lindsay N. Boyers, M. Brainin, M. Brauer, C. Brayne, A. Brazinova, N. Breitborde, H. Brenner, A. Briggs, Jonathan C. Brown, T. Brugha, G. Buckle, L. Bui, G. Bukhman, M. Burch, Ismael Campos Nonato, H. Carabin, Rosario Cárdenas, J. Carapetis, D. Carpenter, V. Caso, Carlos A. Castanda-Orjuela, R. Castro, F. Catalá-López, F. Cavalleri, Jung-Chen Chang, Fiona Charlson, Xuan Che, Honglei Chen, Yingyao Chen, J. Chen, Zhengming Chen, P. Chiang, Odgerel Chimed-Ochir, Rajiv Chowdhury, H. Christensen, C. Christophi, Ting-Wu Chuang, S. Chugh, M. Cirillo, M. Coates, L. Coffeng, M. Coggeshall, A. Cohen, V. Colistro, Samantha M. Colquhoun, Mercedes Colomar, L. Cooper, C. Cooper, Luis M. Coppola, Monica Cortinovis, K. Courville, B. Cowie, M. Criqui, J. Crump, L. Cuevas-Nasu, I. Leite, Kaustubh C Dabhadkar, L. Dandona, R. Dandona, E. Dansereau, P. Dargan, A. Dayama, V. D. L. Cruz-Góngora, S. Vega, D. Leo, L. Degenhardt, B. Pozo-Cruz, R. Dellavalle, Kebede Deribe, D. Jarlais, Muluken Dessalegn, G. deVeber, S. Dharmaratne, M. Dherani, J. Díaz-Ortega, C. Díaz-Torné, D. Dicker, E. Ding, K. Dokova, E. Dorsey, T. Driscoll, L. Duan, H. Duber, Adnan M. Durrani, B. Ebel, K. Edmond, R. Ellenbogen, Yousef M Elshrek, S. Ermakov, H. Erskine, B. Eshrati, A. Esteghamati, Kara Estep, Thomas Fürst, S. Fahimi, A. Fahrion, E. J. Faraon, F. Farzadfar, Derek F J Fay, A. Feigl, V. Feigin, M. Felicio, S. Fereshtehnejad, J. Fernandes, A. Ferrari, T. Fleming, N. Foigt, Kyle Foreman, M. Forouzanfar, F. Fowkes, U. F. Paleo, R. Franklin, N. Futran, L. Gaffikin, K. Gambashidze, F. Gankpé, Francisco Armando Garc-Guerra, A. C. Garcia, J. Geleijnse, B. Gessner, K. Gibney, R. Gillum, S. Gilmour, I. Ginawi, M. Giroud, E. Glaser, S. Goenka, H. G. Dantés, P. Gona, D. González-Medina, C. Guinovart, Rahul Gupta, Rajeev Gupta, R. Gosselin, C. Gotay, A. Goto, H. Gouda, Nicholas Graetz, K. Greenwell, H. Gugnani, D. Gunnell, Reyna A. Gutiiérez, J. Haagsma, N. Hafezi-Nejad, H. Hagan, M. Hagströmer, Y. Halasa, R. Hamadeh, Hannah Hamavid, M. Hammami, Jamie Hancock, G. Hankey, Gillian M. Hansen, H. Harb, Heather C Harewood, J. Haro, Rasmus J Havmoeller, R. Hay, Simon Iain Hay, M. Hedayati, I. B. H. Pi, K. Heuton, P. Heydarpour, Hideki Higashi, M. Híjar, H. Hoek, H. Hoffman, J. Hornberger, H. Hosgood, Mazeda Hossain, P. Hotez, D. Hoy, M. Hsairi, G. Hu, John J Emmanuel Huang, Mark D. Huffman, Andrew Hughes, A. Husseini, Chantal K Huynh, Marissa Iannarone, K. Iburg, B. Idrisov, Nayu Ikeda, K. Innos, M. Inoue, F. Islami, S. Ismayilova, K. Jacobsen, S. Jassal, S. Jayaraman, P. Jensen, V. Jha, G. Jiang, Ying Jiang, J. Jonas, Jonathan C. Joseph, K. Juel, E. Kabagambe, H. Kan, A. Karch, Chante Karimkhani, G. Karthikeyan, N. Kassebaum, Anil Kaul, N. Kawakami, K. Kazanjan, Dhruv S. Kazi, A. Kemp, A. Kengne, A. Keren, M. Kereselidze, Y. Khader, S. Khalifa, E. Khan, G. Khan, Y. Khang, C. Kieling, Y. Kinfu, J. Kinge, Daniel H. Kim, Sungroul Kim, M. Kivipelto, L. Knibbs, A. Knudsen, Y. Kokubo, S. Kosen, Meera Kotagal, M. Kravchenko, S. Krishnaswami, H. Krueger, B. K. Defo, E. Kuipers, B. K. Bicer, Chanda Kulkarni, Veena S. Kulkarni, Kaushalendra Kumar, Ravindra Kumar, G. Kwan, H. Kyu, T. Lai, A. Balaji, R. Lalloo, T. Lallukka, H. Lam, Q. Lan, V. Lansingh, H. Larson, A. Larsson, P. Lavados, A. Lawrynowicz, J. Leasher, Jong-Tae Lee, J. Leigh, M. Leinsalu, R. Leung, Carly E Levitz, Bin Li, Yichong Li, Yongmei Li, Chelsea A Liddell, Stephen S. Lim, G. Lima, M. Lind, S. Lipshultz, Shiwei Liu, Yang Liu, B. Lloyd, K. Lofgren, G. Logroscino, S. London, J. Lortet-Tieulent, P. Lotufo, R. Lucas, R. Lunevicius, R. Lyons, Stefan Ma, V. Machado, Michael F. MacIntyre, M. Mackay, J. MacLachlan, C. Magis-Rodríguez, A. Mahdi, M. Majdan, R. Malekzadeh, S. Mangalam, C. Mapoma, M. Marape, W. Marcenes, Christopher Margono, G. Marks, M. Marzan, J. Masci, M. T. Mashal, F. Masiye, A. Mason-Jones, R. Matzopolous, B. Mayosi, Tasara Mazorodze, J. Mcgrath, A. Mckay, M. Mckee, Abigail McLain, P. Meaney, M. Mehndiratta, Fabiola Mejía-Rodríguez, Y. Melaku, M. Meltzer, Z. Memish, W. Mendoza, G. Mensah, A. Meretoja, F. Mhimbira, T. Miller, E. Mills, Awoke Misganaw, S. Mishra, C. Mock, T. Moffitt, N. Ibrahim, K. Mohammad, A. Mokdad, G. Mola, L. Monasta, J. D. Monis, J. M. Hernandez, M. Montico, T. Montine, M. Mooney, A. Moore, M. Moradi-Lakeh, Andrew E. Moran, R. Mori, J. Moschandreas, W. Moturi, Madeline L Moyer, D. Mozaffarian, U. Mueller, Mitsuru Mukaigawara, Erin C. Mullany, Joseph Murray, A. Mustapha, Paria Naghavi, A. Naheed, K. Naidoo, L. Naldi, D. Nand, V. Nangia, K. Narayan, D. Nash, Jamal T Nasher, C. Nejjari, R. Nelson, M. Neuhouser, S. Neupane, P. Newcomb, L. Newman, C. Newton, Marie Ng, F. Ngalesoni, Grant Nguyen, Nhung T. T. Nguyen, M. I. Nisar, Sandra Nolte, O. Norheim, Rosana E Norman, B. Norrving, L. Nyakarahuka, Shaun Odell, M. O’Donnell, T. Ohkubo, Summer Lockett Ohno, B. Olusanya, S. Omer, John Nelson Opio, O. Orisakwe, K. Ortblad, Alberto Ortiz, M. K. Otayza, A. Pain, J. Pandian, C. Panelo, Jeemon Panniyammakal, C. Papachristou, A. P. Caicedo, S. Patten, G. Patton, V. Paul, B. Pavlin, N. Pearce, C. Pellegrini, David M Pereira, Sophie C. Peresson, R. Perez-Padilla, F. Pérez-Ruiz, N. Perico, A. Pervaiz, K. Pesudovs +499 moresemanticscholar +1 more source
