Results 121 to 130 of about 2,059,704 (313)

2013 documentation initial release : mortality multiple cause-of-death public use record [PDF]

The file layout is separate for US and territories data but both are included in this package. Look for Deaths: Final data for 2013 at http://www.cdc.gov/nchs/data/nvsr/ for other notes about the file.NOTE: A relatively small number of records ...

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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

A Timelier Understanding of Death : Innovative ways to modernize death data include novel technologies, real-world testing, and shared community spaces [PDF]

Death certificates are a powerful tool for understanding how and why people die, providing the most reliable and complete information on ~3 million deaths per year in America. Cause-of-death information is valuable to families and to public health \u2013

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Teaching cause-of-death certification: Lessons from international experience

, 2010
Background and objective: The accuracy of cause-of-death statistics substantially depends on the quality of cause-of-death information in death certificates, primarily completed by medical doctors.
Walker, Sue M., Walker, S, Aung, Eindra, Rao, C, Rao, Chalapati, Aung, E   +5 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The cost, cause and place of death in patients dying with HIV/AIDS and who have access to ART

, 2005
Includes bibliographical references (leaves 48-52).The study aimed to explore the causes of death, the costs involved in these deaths as well as the places where these deaths occurred.
Hellström, Lize
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Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Causas múltiples de muerte

Revista Cubana de Higiene y Epidemiología, 1998
Se presenta un estudio de causas múltiples de muerte, en la población cubana de 1 año y más de edad. La información se obtuvo de una muestra de 2 036 defunciones ocurridas durante 4 meses consecutivos en 22 municipios del país.
Norma Eneida Ríos Massabot, Ana Consuelo Mesa Machado, Arnaldo Tejeiro Fernández   +2 more
doaj  

Leading causes of death, 1900-1998 [PDF]

The tables on the following pages represent the leading causes of death in the death registration area for the period 1900-1932 and the United States for the period 1933-1998.

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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source