Results 141 to 150 of about 2,059,704 (313)
Cause-specific contributions to sex differences in adult mortality among whites and African Americans between 1960 and 1995 [PDF]
The purpose of this paper is to describe trends in sex differences in mortality in young adulthood and in middle age among African Americans and whites in the United States between 1960 and 1995.
Greg L. Drevenstedt, Irma Elo
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Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
National Violent Death Reporting System: Web Coding Manual: Version 6.0 [2022-01-18]
Version 6.0, revision date: January 18, 2022The NVDRS Coding Manual is a reference document to be used for defining cases and variables, entering data, and checking data once they are entered.
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Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Review of Infant and Child Death in a Tertiary Care Teaching Institute in Surat
Background: A systematic review of child Death (CDR) was required to improve the quality of neonatal health care to avoid more deaths in that particular group especially.
Rajiv Kumar Prasad +3 more
doaj
Estimate of selected comparability of ratios dased on dual coding of 1976 death certificates by the eighth and ninth revisions of the International Classification of Diseases [PDF]
One of the efforts to maintain the tradition of progress in the classification of diseases has Izccn the practice, begun in 1900, to revise about every 10 years what is now the International Classification of Diseases (ICD).
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Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source

