Results 141 to 150 of about 4,353,386 (346)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Critical Periods and Causes of Death in Avian Embryonic Development [PDF]
, 1949 Alexis L. Romanoff
openalex +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Mortality in Central and Eastern Europe
Demographic Research, 2004 While, during several decades, unfavourable trends in mortality were quite similar in Central Europe and in the former USSR, in the most recent years, these two parts of Europe are diverging.
doaj
Neonatal Deaths in Rural Southern Tanzania: Care-Seeking and Causes of Death [PDF]
, 2012 Mwifadhi Mrisho +8 more
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
A RETROSPECTIVE STUDY OF DEATHS AMONG PARTICIPANTS IN THE LIQUIDATION OF THE CONSEQUENCES OF THE ACCIDENT AT THE CHORNOBYL NPP DUE TO INJURY, POISONING AND CERTAIN OTHER CONSEQUENCES OF EXTERNAL CAUSES (2000–2020) [PDF]
N. Gunko +6 more
openalex +1 more source
Lung cancer new leading cause of death for women in developed countries: Data reflects increased rates of smoking [PDF]
, 2015 Carrie Printz
openalex +1 more source
Knowledge on inquest and cause of death– A study among doctors at teaching hospital Jaffna
, 2022 U. Mayorathan +4 more
openalex +2 more sources