Results 151 to 160 of about 5,086,231 (350)

Mortalidade infantil em município da região Centro-Oeste Paulista, Brasil, 1990 a 1992

Revista de Saúde Pública
INTRODUÇÃO: A mortalidade infantil em Presidente Prudente, SP (Brasil), foi estudada no período de 1990 a 1992, a partir de aplicação de métodos para obtenção de diagnóstico coletivo que orientassem a identificação e escolha de estratégias de controle de
Jaime de O. Gomes, Augusto H. Santo
doaj  

Cardiovascular mortality: quality diagnostics analysis and causal statistics of lethal outcomes [PDF]

Саратовский научно-медицинский журнал, 2011
The high cardiovascular mortality (CVM) proves the necessity of verification analysis of cardiovascular death causes. The research goal is to determine the quality, facilities and peculiarities of cardiovascular diseases (CVD) of postmortem diagnostics ...
Nikulina N.N.
doaj  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Hollywood's misrepresentation of death: A comparison of overall and by-gender mortality causes in film and the real world [PDF]

arXiv
The common phrase 'representation matters' asserts that media has a measurable and important impact on civic society's perception of self and others. The representation of health in media, in particular, may reflect and perpetuate a society's disease burden.
arxiv  

The Cause of Death [PDF]

Journal of the Royal Society of Medicine, 1986
openaire   +3 more sources

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Diferenciais geográficos, socioeconômicos e demográficos da qualidade da informação da causa básica de morte dos idosos no Brasil

Cadernos de Saúde Pública
Identificaram-se diferenciais geográficos e socioeconômicos do padrão de qualidade da informação sobre a causa básica de morte dos idosos no Brasil.
Solange Kanso, Dalia Elena Romero, Iúri da Costa Leite, Edgar Nunes de Moraes   +3 more
doaj  

Coding historical causes of death data with Large Language Models [PDF]

arXiv
This paper investigates the feasibility of using pre-trained generative Large Language Models (LLMs) to automate the assignment of ICD-10 codes to historical causes of death. Due to the complex narratives often found in historical causes of death, this task has traditionally been manually performed by coding experts. We evaluate the ability of GPT-3.5,
arxiv  

SYPHILIS AND ANEURYSM: Age and Sex Incidence and Cause of Death in Aortic Aneurysm [PDF]

, 1925
E. M. Brockbank
openalex   +1 more source