Results 161 to 170 of about 5,086,231 (350)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Cause and Prevention of Death from Chloroform [PDF]

Jessica Snow
openalex   +1 more source

A CASE OF FRACTURE OF THE SKULL CAUSING DEATH AFTER ELEVEN YEARS [PDF]

, 1923
Justine R. Smith, Mohamed Emara
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Review of Infant and Child Death in a Tertiary Care Teaching Institute in Surat

National Journal of Community Medicine, 2017
Background: A systematic review of child Death (CDR) was required to improve the quality of neonatal health care to avoid more deaths in that particular group especially.
Rajiv Kumar Prasad, Rachana Prasad, Vibhuti Vaghela, Chetan B Chovatiya   +3 more
doaj  

Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016–40 for 195 countries and territories

The Lancet, 2018
Kyle Foreman, N. Marquez, A. Dolgert, K. Fukutaki, N. Fullman, Madeline McGaughey, Martin A Pletcher, Amanda E. Smith, Kendrick Tang, Chun-wei Yuan, Jonathan C. Brown, Joseph Friedman, Jiawei He, K. Heuton, Mollie Holmberg, Disha J Patel, P. Reidy, A. Carter, Kelly M. Cercy, Abigail Chapin, Dirk Douwes-Schultz, Tahvi D Frank, Falko Goettsch, Patrick Y. Liu, Vishnu Nandakumar, M. Reitsma, Vincent P Reuter, Nafis Sadat, Reed J. D. Sorensen, V. Srinivasan, R. Updike, H. York, Alan D. Lopez, R. Lozano, Stephen S. Lim, A. Mokdad, S. Vollset, C. Murray   +37 more
semanticscholar   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Mortality in Central and Eastern Europe

Demographic Research, 2004
While, during several decades, unfavourable trends in mortality were quite similar in Central Europe and in the former USSR, in the most recent years, these two parts of Europe are diverging.
doaj  

Importance of Tabulating Multiple Causes of Death

, 1940
Theodore A. Janssen
openalex   +2 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source