Results 141 to 150 of about 5,176,576 (252)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Faces and causes of Roma marginalization: Experiences from Hungary

, 2014
The "Faces and Causes of Roma Marginalization in Local Communities" inquiry explored the economic, political, demographic, and social forces at municipal and community level which shape practices and consequences of social exclusion and potential ...
Virág, Tünde, Váradi, Monika
core  

Transition in the Composition of Maternal Mortality in Korea: Implications for Extremely Low Fertility Societies. [PDF]

J Korean Med Sci
Han BR, Oh JW, Yoon SJ, Seo J, Min HS, Ahn KH, Choe SA.   +6 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

A Comparative Analysis of Aging Across Causes of Death. [PDF]

Evol Appl
Sorci G, Faivre B.
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Understanding stillbirths and maternal deaths in Pakistan: evidence from a national household survey. [PDF]

J Glob Health
Nausheen S, Ariff S, Umer M, Qadir Z, Nooruddin S, Habib MA, Rizvi A, Khan A, Chauhadry IA, Kalter HD, Soofi SB, Black RE, Bhutta ZA.   +12 more
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Parents' beliefs on the causes of child maltreatment

, 2016
The present study presents an analysis of the beliefs of a sample of Portuguese parents on the causes of child maltreatment as well as an analysis of the variability factors of such beliefs.
Calheiros, M. M.
core  

Patterns and Causes of Adult Blindness in a Tertiary Ophthalmic Center in Somalia: The Burden of Trauma-Related Visual Loss. [PDF]

Clin Ophthalmol
Calisir K, Kadiye MS.
europepmc   +1 more source