Results 231 to 240 of about 9,663,842 (303)

Causes justes, causes célèbres

, 2001
openaire   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Key Techniques and Outcome Analysis of Endoscopic Mastoid Revision Surgery. [PDF]

Med Sci Monit
Zeng N, Yang Q, Wu J, Tang M, Jin Y, Zhang L, Hu J, Hong S, Zuo X, Yan S.   +9 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

F18-FDG PET-CT in immune checkpoint inhibitor-associated acute interstitial nephritis: what is the diagnostic value? [PDF]

Clin Kidney J
Lyrio RMDC, Narvaez VDC, Chavez CCN, Refai OA, Bold M, Leung N, Herrmann SM.   +6 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Understanding and Mitigating Bleeding Risks in Extracorporeal Cardiopulmonary Resuscitation. [PDF]

JACC Asia
Zhou G, Lu Q.
europepmc   +1 more source

Management of male osteoporosis in primary care: clinical approach and pharmacotherapy. [PDF]

Singapore Med J
Poh SXJ, Choong SD, Gani LU, Chua ALA.
europepmc   +1 more source

Fermented foods consumption, all-cause, and cause-specific mortality: a meta-analysis of prospective cohort studies. [PDF]

Front Nutr
Matalas A, Panagiotakos D, Fardet A, Savary-Auzeloux I, Chassard C, Praćer S, Vergères G, Paveljšek D.   +7 more
europepmc   +1 more source

Epidemiological pattern of death and causes of death in registered immigrants of Northeast Iran during the 2013-2023: a cross-sectional study. [PDF]

BMC Public Health
Eslami S, Farkhani EM, Sadeghi M, Andish M, Khodadadi N, Dehghani M.   +5 more
europepmc   +1 more source