Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Temporal trends in the causes of in-hospital cardiac arrest: a retrospective observational cohort study on the limitations of the current alert system at a tertiary hospital in Korea. [PDF]
BMJ OpenLee JM +12 more
europepmc +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Community Preventive Services Task Force Recommends Interventions to Address Leading Causes of Death in Rural Settings. [PDF]
Public Health RepHarmon S +5 more
europepmc +1 more source
Cause of death following revision for periprosthetic joint infection or major aseptic revision in total hip and knee arthroplasty. [PDF]
J Bone Jt InfectKristensen NK +4 more
europepmc +1 more source
Maternal near miss incidence ratio, its causes and risk factors in East Africa: a systematic review and meta-analysis. [PDF]
Reprod HealthGeremew AB +4 more
europepmc +1 more source
How frailty index impacts death in chronic kidney disease: A retrospective observational investigation. [PDF]
PLoS OneXiong M, Lu X.
europepmc +1 more source
Before depression in diabetes is attributed to polyneuropathy, all other causes must be ruled out. [PDF]
Future Sci OAFinsterer J.
europepmc +1 more source