Results 101 to 110 of about 2,938,549 (351)

Malignant mesothelioma in a cohort of asbestos insulation workers: clinical presentation, diagnosis, and causes of death. [PDF]

, 1988
Joseph Ribak, Ruth Lilis, Yota Suzuki, Louis A. Penner, Irving J. Selikoff   +4 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Natural, unnatural, and cause-specific mortality among current psychiatric inpatients: a systematic review and meta-analysisResearch in context

EClinicalMedicine
Summary: Background: Mortality in psychiatric hospitals is both elevated and poorly understood. We aimed to address a knowledge gap about cause-specific mortality among current psychiatric inpatients using a meta-analytic synthesis of primary research ...
Helena Angel-Scott, Ashna Basu, Allyson Tai, Pramudie Gunaratne, Patrick Bolton, Jackie Curtis, Grant Sara, Matthew Large   +7 more
doaj   +1 more source

Hospital-Based Mortality in Federal Capital Territory Hospitals-Nigeria, 2005- 2008

The Pan African Medical Journal, 2012
BACKGROUND: Cause-specific mortality data are important to monitor trends in mortality over time. Medical records provide reliable documentation of the causes of deaths occurring in hospitals.
Nykiconia Preacely, Oladayo Biya, Saheed Gidado, Halima Ayanleke, Mohammed Kida, Moses Akhimien, Aisha Abubakar, Ibrahim Kurmi, Ikeoluwapo Ajayi, Patrick Nguku, Henry Akpan   +10 more
doaj   +1 more source

Validity of verbal autopsy method to determine causes of death among adults in the urban setting of Ethiopia

BMC Medical Research Methodology, 2012
Background Verbal autopsy has been widely used to estimate causes of death in settings with inadequate vital registries, but little is known about its validity.
Misganaw Awoke, Mariam Damen Haile, Araya Tekebash, Aneneh Aderaw   +3 more
doaj   +1 more source

Cause-specific contributions to sex differences in adult mortality among whites and African Americans between 1960 and 1995 [PDF]

The purpose of this paper is to describe trends in sex differences in mortality in young adulthood and in middle age among African Americans and whites in the United States between 1960 and 1995.
Greg L. Drevenstedt, Irma Elo
core  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Results and observations from the reconstruction of continuous time series of mortality by cause of death: Case of West Germany, 1968-1997.

Demographic Research, 2009
Though many countries have been collecting cause-of-death information from death certificates for more than a century, these valuable data sources remain underexplored.
Marketa Pechholdova
doaj  

Causes and Risk Factors for Maternal Mortality in Rural Tanzania - Case of Rufiji Health and Demographic Surveillance Site (HDSS) [PDF]

Complications of childbirth and pregnancy are leading causes of death among women of reproductive age. Developing countries account for 99% of maternal deaths.
Illah, Evance, Kahn, Kathleen, Masanja, Honorati, Mbaruku, Godfrey   +3 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source