Results 241 to 250 of about 2,938,549 (351)

Main Cause of Children's Deaths in Indigenous Wayuu Community from Department of La Guajira: A Research Developed through Data Mining Use

, 2019
Isaura Esther Solano Núñez, David Suarez   +1 more
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Structure of Comorbidities and Causes of Death in Patients with Atrial Fibrillation and Chronic Obstructive Pulmonary Disease. [PDF]

J Clin Med
Kotlyarov S, Lyubavin A.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

A hierarchy of causes of death in senescent C. elegans

Wang H, Kern CC, Nguyen Hong C, Saez Allende A, Qiao J, Zhang A, Fan Y, Ezcurra M, Gems D.   +8 more
europepmc   +1 more source

Causes of Death Among US Medical Residents.

JAMA Netw Open
Yaghmour NA, Bynum WE, Hafferty FW, Könings KD, Richter T, Brigham TP, Nasca TJ.   +6 more
europepmc   +1 more source

Mortality and Causes of Death in Boys and Men Born With Hypospadias: A Swedish Population-Based Cohort Study. [PDF]

Urol Pract
Phillips L, Tettamanti G, Nordgren A, Skarin Nordenvall A, Nordenskjöld A.   +4 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source