Results 61 to 70 of about 167,241,951 (289)

Competing causes of death: A death certificate study [PDF]

Journal of Clinical Epidemiology, 1997
Despite the widespread interest in competing causes of death, empirical information on interrelationships between causes of death is scarce. We have used death certificate information to estimate the prevalence of competing causes of death at the moment of dying from specific underlying causes of death.In a stratified sample of 5975 deaths occurring in
Mackenbach, J. P., Kunst, A. E., Lautenbach, H., Oei, Y. B., Bijlsma, F.   +4 more
openaire   +4 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Mortality in Moscow and other megacities of the world: similarities and differences

Демографическое обозрение, 2017
This paper is devoted to the comparison of mortality by cause of death in Moscow and other megacities of the world since 1990. The selection of megacities was determined by the availability of detailed mortality data in the selected period.
Evgeny Andreev, Ekaterina Kvasha, Tatiana Kharkova   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Analýza faktorů asociovaných s vícečetnými příčinami smrti v Česku v roce 2018 pomocí XGBoost regrese a metody SHAP

Demografie
This study focuses on the factors that are associated with recording multiple causes as the cause of death in Czechia. An XGBoost multiple regression is used in the analysis and its results are interpreted with SHAP values.
Bety Ukolova, Boris Burcin
doaj   +1 more source

Survival rate and death risk for associated pulmonary arterial hypertension: A retrospective population-based study [PDF]

Precision and Future Medicine
Purpose This study aimed to assess the survival rate (SR) and death risk for associated pulmonary arterial hypertension (aPAH; 10th revision of the International Statistical Classification of Diseases [ICD-10], I27.2) in Koreans.
Sujin Kim, Shin Yi Jang, Soo Yeon Lee, Su Ra Seo, Seonju Yi, Chang-Kwan Lee, Eun Jeong Cho, Kyeongsug Kim   +7 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Differences in Causes of Death among the Elderly in Four Regions of the Russian Federation: Retrospective Study

Российский журнал гериатрической медицины
OBJECTIVE. To identify and discuss the causes of death among the elderly in the four regions of the Russian Federation, using medical death certificate (MDC) data.MATERIALS AND METHODS.
O. V. Zayratyants, I. V. Samorodskaya, E. P. Kakorina, O. L. Barbarash, I. F. Mingazov   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source