Results 41 to 50 of about 1,173,637 (219)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Analýza faktorů asociovaných s vícečetnými příčinami smrti v Česku v roce 2018 pomocí XGBoost regrese a metody SHAP

open access: yesDemografie
This study focuses on the factors that are associated with recording multiple causes as the cause of death in Czechia. An XGBoost multiple regression is used in the analysis and its results are interpreted with SHAP values.
Bety Ukolova, Boris Burcin
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

From Macro-Statistics to Family Reconstitution Data. Causes of Death in Hungary (Sources and Databases — 19th and Early 20th Centuries)

open access: yesHistorical Life Course Studies
This paper presents Hungarian sources that provide information on the causes of death at both individual and aggregate levels. It demonstrates how causes of death appeared in parish records from the early 19th century onwards, alongside denominational ...
Péter Őri, Levente Pakot
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

RECONSTRUCTION OF THE CONTINUITY OF CAUSE-SPECIFIC MORTALITY TRENDS FOR THE REPUBLIC OF MOLDOVA [PDF]

open access: yesEconomy and Sociology, 2015
The paper presents the stages of reconstruction of the continuity of cause-of-death time series for Moldova based on a special method developed by French demographers Jacques Vallin and France Meslé (Institut national d’études démographiques, INED).
Olga PENINA
doaj  

Intrahepatic cholestasis of pregnancy and associated causes of death: a cohort study with follow-up of 27–46 years

open access: yesBMC Women's Health, 2018
Background The aim of this study was to determine whether intrahepatic cholestasis of pregnancy (ICP) is associated with causes of death during on average 35 years follow-up after the delivery. Methods The study population comprised 571 women with ICP in
Suvi-Tuulia Hämäläinen   +3 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Analysis of the Underlying and Multiple Causes of Death for the Kuwaiti Population 40 years or over; Part II: Causes

open access: yesJournal of High Institute of Public Health, 2009
Background: Death rarely results from a single cause; it can be caused by a variety of factors. Multiple causes of death (MCD) can provide information about the associations between causes of death revealing common combinations of conditions.
Kamel Alsaleh   +4 more
doaj   +1 more source

Methodological aspects of constatation of Alzheimer disease as a cause of death in the elderly

open access: yesОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2020
In connection  with the increase in the proportion  of the elderly population,  the multifaceted adverse significance of Alzheimer’s  disease has recently been widely discussed, including its role as a cause of death.
N. G. Neznanov, L. S. Kruglov
doaj   +1 more source

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