Results 71 to 80 of about 19,971 (265)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Ingestion of caustic substances and its complications
CONTEXT: Caustic substances cause tissue destruction through liquefaction or coagulation reactions and the intensity of destruction depends on the type, concentration, time of contact and amount of the substance ingested.
Rui Celso Martins Mamede +1 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Addendum to a paper of Craig and Goodman
In [1], Craig and Goodman develop the geometrical optics solution of the linearized Korteweg-deVries equation away from caustic, or turning, points. Here we develop an analogous solution valid at caustic points.
Arthur D. Gorman
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Caustic Object Construction Based on Multiple Caustic Patterns. [PDF]
Inverse caustic problem, that is computing the geometry of a reflector and/or refractor based on a given caustic pattern, is currently not widely studied. In this paper, we propose a technique to solve the inverse caustic problem in which we compute the geometry of a semi-transparent homogeneous refractive object (caustic object) given a directional ...
Tandianus, Budianto +2 more
openaire +2 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
On the caustic of a convex mirror
Consider a smooth positively curved ovaloid \(M^ n\) in Euclidean \((n+1)\)-space and a point 0 in the interior of \(M^ n\). The caustic of the system \(\{M^ n,0\}\) is defined as the envelope of the light rays emanating from 0 after reflection on the `mirror' \(M^ n\).
Georgiou, C. +2 more
openaire +3 more sources
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Current modulations, current spikes, and current horns, are observed in a range of accelerator physics applications including strong bunch compression in Free Electron Lasers and linear colliders, trains of microbunching for terahertz radiation ...
T. K. Charles +2 more
doaj +1 more source

