Results 141 to 150 of about 6,216 (303)
Advanced Science, EarlyView.An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao +11 more
wiley +1 more source
, 2017 Studies focusing cave fauna on granitic caves are relatively rare when compared to carbonatic ones and no one considered replicas in the sampling to test fauna distribution patterns.
Resende, Leonardo P.A. +11 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei +11 more
wiley +1 more source
Advanced Science, EarlyView.The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
wiley +1 more source
Characterization of anuran fauna inside caves in Brazil
Biota NeotropicaAbstract: The natural underground environment has unique characteristics when compared to surface environments. These environments feature a reduced complexity food web that includes organisms such as anuran amphibians. This study examines the occurrence of Neotropical anurans in Brazilian caves, utilizing taxonomic, geographic, geological, and ...
Vinícius da Fontoura Sperandei +2 more
openaire +2 more sources
Macrophage Extracellular Traps in Immunity and Cancer
Advanced Science, EarlyView.As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Extinct steppe-tundra fauna from Cuvier 1 and Cuvier 2 cave at Fouvent-le-Bas (Haute-Saône, France)
, 2022 International audienceStudies of the fauna from the Cave « Cuvier 1 » and the various levels of the cave « Cuvier 2 » at Fouvent-le-Bas have encouraged artists and scientists to reconstruct the extinct fauna of large mammals, carnivores and microfauna ...
Roger, T. +5 more
core