Results 221 to 230 of about 6,216 (303)

Gray wolves in an anthropogenic context on a small island in prehistoric Scandinavia. [PDF]

Proc Natl Acad Sci U S A
Girdland-Flink L, Bergström A, Storå J, Ersmark E, Apel J, Krzewińska M, Dalén L, Götherström A, Skoglund P.   +8 more
europepmc   +1 more source

From Label‐Free Multiphoton Imaging to Pathological Reports: A Vision‐Language Breast Cancer Margin Pathological Diagnosis System

Advanced Science, EarlyView.
MarginPath is a novel vision‐language system that automates breast cancer margin assessment using a single label‐free multiphoton microscopy image. By integrating tumor‐associated collagen signatures with virtual H&E imaging, it generates accurate margin heatmaps and comprehensive diagnostic reports.
Shu Wang, Jingze Su, Xiahui Han, Deyong Kang, Xiao Zhang, Fei Xu, Changzu Liu, Junlin Pan, Xingfu Wang, Qiaohui Zhan, Aimin Wang, Feng Huang, Heping Cheng, Wenxi Liu, Ruolan Lin, Jianxin Chen   +15 more
wiley   +1 more source

Surface geoenvironments shape organic matter inputs in iron-ore caves of Carajás, southeastern Amazonia. [PDF]

PLoS One
Reis LS, Felix Guimarães JT, de Sá CYG, Bernard E, Ruiz Pessenda LC, Gastauer M, de Oliveira PE.   +6 more
europepmc   +1 more source

PancDS in Real‐World Practice: A Prospective Multicenter Validation of a Clinical Decision‐Support System Bridging Experience Gaps in Pancreatic Lesion Diagnosis

Advanced Science, EarlyView.
A biomimetic artificial intelligence system, PancDS, has been developed to distinguish pancreatic ductal adenocarcinoma from mass‐forming pancreatitis by adaptively integrating clinical data, radiomics, and deep learning features. Validated across multicenter, reader‐study, and prospective settings, PancDS improves diagnostic accuracy, particularly for
Zhibo Wang, Weinuo Qu, Wenwen Cai, Chuhuai Wang, Chenxi Lyu, Qingguo Xie, Qian Chu, Yaqi Shen, Peng Xiao, Feng Li, Qingpeng Zhang, Jiali Li, Jeong Min Lee, Zhen Li   +13 more
wiley   +1 more source

Insights from the Dalberto Teixeira Pombo (DTP) Arthropod Collection - I. Revealing the Hidden Diversity of Terrestrial Cave Arthropods in the Azores. [PDF]

Biodivers Data J
Crespo LCF, Pereira F, R Amorim I, Borges PAV.   +3 more
europepmc   +1 more source

Reprogramming the Immune Landscape of Inflammatory Breast Cancer

Advanced Science, EarlyView.
Inflammatory breast cancer is the most lethal subtype of breast cancer and is characterized by an immunosuppressive tumor microenvironment (TME) driven by a complex network of immune cells and inflammatory cytokines, contributing to its aggressiveness and treatment challenges. Immune checkpoint inhibitors, either alone or in combination, show potential
Verena Martinez‐Rodriguez, Suguru Ogata, Xiaoping Wang, Naoto T. Ueno   +3 more
wiley   +1 more source

A 75,000-y-old Scandinavian Arctic cave deposit reveals past faunal diversity and paleoenvironment. [PDF]

Proc Natl Acad Sci U S A
Walker SJ, Boilard A, Henriksen M, Lord E, Robu M, Buylaert JP, Beijersbergen LMT, Halvorsen LS, Cintrón-Santiago AM, Onshuus EK, Cockerill CA, Ujvari G, Palcsu L, Temovski M, Maccali J, Linge H, Olsen J, Aksnes S, Bertheussen A, Lygre O, Alsos IG, Dalén L, Star B, Hufthammer AK, van Kolfschoten T, Lauritzen SE, Lødøen TK, Boessenkool S.   +27 more
europepmc   +1 more source

Noninvasive Characterization of Tumor Heterogeneity in HNSCC: From Clinical Utility to Biological Correlates

Advanced Science, EarlyView.
This study establishes a CT‐based radiomics framework to quantify intratumoral heterogeneity (ITH) in HNSCC. Using unsupervised clustering, tumor ROIs and VOIs are analyzed to calculate 2D/3D ITH scores. The score shows strong predictive value for prognosis and immunotherapy response, and is associated with tumor metabolism and immune microenvironment,
Xinwei Chen, Rui Liu, Yuan Zhou, Yin Xiao, Chengmin Feng, Lin Chen, Yanshi Li, Mengna Wang, Zhaobo Cheng, Yuxi Luo, Long Liu, Lijing Niu, Yue Xiang, Juan Peng, Guohua Hu, Min Pan   +15 more
wiley   +1 more source

On a new genus and species of karst-dwelling freshwater crab (Crustacea, Brachyura, Potamidae) from Peninsular Malaysia. [PDF]

Zookeys
Tan ZW, Ooi Q, Ng PKL.
europepmc   +1 more source

CEBPG‐Mediated Palmitic Acid Adaptation of Cancer‐Associated Fibroblasts Drives Metastasis of Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan, Yitong Li, Yufei Wu, Xiao Yang, Rui Li, Hui Zhao, Zhengjun Shang   +6 more
wiley   +1 more source