Results 51 to 60 of about 64,001 (226)

Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations [PDF]

, 2015
PurposeThe phenotypic manifestations of cerebral cavernous malformation disease caused by rare PDCD10 mutations have not been systematically examined, and a mechanistic link to Rho kinase-mediated hyperpermeability, a potential therapeutic target, has ...
Zhang, Lingjiao, Jorge Marcondes de Souza, Stockton, Rebecca A, Wang Min, Akers, Amy L, Carol J. Gallione, Changbin Shi, Shenkar, Robert, Rebeiz, Tania, Robert Shenkar, Min, Wang, Awad, Issam A, Marcondes de Souza, Jorge, Douglas A. Marchuk, Lingjiao Zhang, Gallione, Carol J, Abdul Ghani Mikati, David A. McDonald, Marchuk, Douglas A, Autumn Rorrer, Shi, Changbin, Cecilia Austin, Amy L. Akers, Connie Lee, McDonald, David A, Lee, Connie, Murat Gunel, Tania Rebeiz, Rebecca A. Stockton, Issam A. Awad, Mikati, Abdul Ghani, Rorrer, Autumn, Gunel, Murat, Austin, Cecilia   +33 more
core   +1 more source

Diagnosis and treatment of cavernous malformations of the spine and spinal cord

Ukrainian Neurosurgical Journal, 2012
Introduction. This study was conducted in order to clarify structural features of cavernous malformations, to develop a technique for their surgical treatment and to analyze treatment outcomes.Methods.
Eugene Slynko, Alexander Zolotoverkh, Vadim Verbov, Ruslan Pishanov   +3 more
doaj   +1 more source

Upper bound limit analysis of coral reef limestone cavern roof stability incorporating a tension‐shear failure mechanism with tensile‐strength cut‐off

Deep Underground Science and Engineering, EarlyView.
For the roof of coral reef limestone caverns, a novel tension‐shear composite failure mechanism was developed. The most critical tensile crack model was identified using a hybrid optimization algorithm, and the stability of the cavern roof was analyzed accordingly.
Dongsheng Xu, Chenxu Li, Chuantan Hou
wiley   +1 more source

Far-Lateral Approach for Medullary Cavernous Malformation: 2-Dimensional Operative Video.

, 2020
Medullary cavernous malformations are the rarest subtype of brainstem cavernous malformation and are associated with a high degree of morbidity. Selection of surgical candidates is critical, and cases are most favorable when the cavernous malformation ...
Spetzler, Robert F, Hendricks, Benjamin K   +1 more
core   +1 more source

Analysis of lining force transmission coefficient and surrounding rock displacement in lined rock caverns for underground gas storage

Deep Underground Science and Engineering, EarlyView.
This study derives an explicit expression for the lining force transmission coefficient of underground gas storage lined rock caverns (LRCs) via the complex variable function method, considering the displacement release coefficient. Taking the 1‰ tensile strain of surrounding rock as the criterion to determine lining thickness, it systematically ...
Yaohui Li, Jianping Yang, Weizhong Chen
wiley   +1 more source

Giant cavernous malformation in the child: Case presentation [PDF]

, 2012
Cerebral cavernous malformations (CCMs) are rare lesions that occurs 5 to 13% of all intracranial vascular malformations, develop in 0.02-0.13% of the population. Extra axial cavernous Malformations are even more rare and estimated to be 0.4 to 2% of all
Shrestha, Rajendra, Pradhan, Reeka, Chao, You   +2 more
core   +1 more source

Venous Malformations in Childhood: Clinical, Histopathological and Genetics Update

Dermatopathology, 2021
Our knowledge in vascular anomalies has grown tremendously in the past decade with the identification of key molecular pathways and genetic mutations that drive the development of vascular tumors and vascular malformations.
Isabel Colmenero, Nicole Knöpfel
doaj   +1 more source

Epileptogenic lesions in the Australian epilepsy project: A harmonized 3‐T magnetic resonance imaging protocol and its diagnostic yield

Epilepsia, EarlyView.
Abstract Objective Detection of epilepsy‐causing structural brain lesions on magnetic resonance imaging (MRI) is critical for diagnosis, prognosis, and treatment planning in people with epilepsy. We aimed to establish an epilepsy‐directed multisite harmonized 3‐T MRI acquisition protocol for the Australian Epilepsy Project (AEP) and describe the ...
David N. Vaughan, David F. Abbott, Amanda Anderson, Greg Fitt, Suyi Ooi, Heath Pardoe, Donna Parker, Yuliya Perchyonok, Eric Pierre, Chris Kokkinos, Robert E. Smith, Michael Stewart, Bahman Tahayori, Chris Tailby, Graeme D. Jackson, the Australian Epilepsy Project Investigators, Zanfina Ademi, Patrick Kwan, Karen Oliver, Mangor Pedersen   +19 more
wiley   +1 more source

Surgical Treatment of Cavernous Sinus Cavernomas: Evidence from Vietnam

Reports, 2020
Cavernous sinus cavernomas, a rare vascular malformation, represents 3% of all benign cavernous sinus tumors. Both clinical and radiological signs are important for differentiating this condition from other cavernous sinus diseases. The best treatment is
Duc-Anh Nguyen, Hao The Nguyen, Thang Van Duong, Binh Hoa Pham, Hoang-Long Vo   +4 more
doaj   +1 more source

Detection of interictal epileptiform discharges using multiple bilateral insertions of a newly developed microcatheter‐compatible endovascular electroencephalogram electrode: A clinical feasibility trial

Epilepsia Open, EarlyView.
Abstract Objective To assess the feasibility, technical performance, and safety of a novel endovascular electroencephalogram (eEEG) electrode, EP‐01, designed for minimally invasive seizure localization in patients with drug‐resistant epilepsy. Methods This single‐center, prospective, exploratory trial enrolled five patients with drug‐resistant ...
Kota Araki, Yosuke Masuda, Ayataka Fujimoto, Mitsuyo Nishimura, Hisayuki Hosoo, Hiroki Ishida, Takashi Enokizono, Kensuke Kawai, Eiichi Ishikawa, Yuji Matsumaru   +9 more
wiley   +1 more source