Results 61 to 70 of about 138,530 (207)

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song, Yan Liu, Shifeng Zhao, Cheng Zhu, Hongchang Guo, Jin Chang, Jun Kang   +6 more
wiley   +1 more source

Numerical Simulation of Cavitating Water Jet by a Compressible Mixture Flow Method

Journal of Fluid Science and Technology, 2011
Concerned on the numerical simulation of high-speed water jet accompanied with intensive cavitation, a practical compressible mixture flow method is developed by coupling a simplified estimation of bubble cavitation and a flexible compressible flow ...
Guoyi PENG, Seiji SHIMIZU, Shigeo FUJIKAWA   +2 more
doaj   +1 more source

Growth and Collapse of Cavitation Bubbles : Distribution Change of Cavitation Nuclei due to the Collapse of Cavitation Bubbles

Bulletin of JSME, 1984
The growth and collapse of cavitation bubbles are observed in distilled water using a hydro shock tube which alternately generates low The cavitation bubbles pressure and high pressure in the test section. are fragmentized into numerous small bubbles (so called nuclei) after their collapse.
MATSUMOTO, Yoichito, AOKI, Makoto
openaire   +2 more sources

Mixture segregation by an inertial cavitation bubble [PDF]

Ultrasonics Sonochemistry, 2007
Pressure diffusion is a mass diffusion process forced by pressure gradients. It has the ability to segregate two species of a mixture, driving the densest species toward high pressure zones, but requires very large pressure gradients to become noticeable. An inertial cavitation bubble develops large pressure gradients in its vicinity, especially as the
Grossier, R., Louisnard, Olivier, Vargas, Y.   +2 more
openaire   +3 more sources

Prediction of far-field acoustic emissions from cavitation clouds during shock wave lithotripsy for development of a clinical device

, 2013
This study presents the key simulation and decision stage of a multi-disciplinary project to develop a hospital device for monitoring the effectiveness of kidney stone fragmentation by shock wave lithotripsy (SWL).
A. R. Jamaluddin, Turangan, C.K., Jamaluddin, A.R., C. K. Turangan, Ball, G.J., P. R. White, White, P.R., G. J. Ball, Leighton, T. G., T. G. Leighton   +9 more
core   +1 more source

Glutaminolysis Blockade‐Empowered Bimodal Nanodepot for Spatially Complementary Sono‐Thermal Ablation via PANoptosis and STING Activation Against Large Tumors

Advanced Science, EarlyView.
An injectable bimodal TCPD nanodepot disrupts glutaminolysis and TCA metabolism, sensitizing large tumors to spatially complementary sono‐thermal ablation for complete treatment coverage. This intervention induces mitochondrial and endoplasmic reticulum dysfunction, genotoxicity, and NAD+ depletion, converging to trigger PANoptosome assembly and ...
Yi‐Ming Liu, Juan Qin, Si‐Yuan Wu, Xue‐Zhen Zhu, Yun‐Fei Cai, Pei‐Yao Sun, Hao Yang, Xing‐Yue Wang, Shu Li, Duo Wang, Hai‐Dong Zhu   +10 more
wiley   +1 more source

On the Operation of T-mixer Chemical Reactors in the Cavitation Regime

Chemical Engineering Transactions, 2019
The apparition of the cavitation phenomenon in chemical precipitation reactors with rapid micromixing can significantly affect the elaboration process.
Khaled Oualha, Mounir Ben Amar, Jean-Philipe Passarello, Andrei Kanaev   +3 more
doaj   +1 more source

Topological Quantum Biomaterials Enable Pyroptosis‐Senescence Coupling for Enhanced Colorectal Cancer Therapy

Advanced Science, EarlyView.
This work reports conceptually unprecedented topological quantum biomaterials derived from engineered Pd3Sn nanostrips for oncological applications. Their near‐Fermi‐level electronic architecture and superior interfacial charge transport facilitate ultrasound‐amplified redox reactions and efficient ROS generation.
Zilu Chen, Kun Mei, Yan Yang, Mengna Xu, Xinyue Dai, Renjun Gu, Fuqiong Zhou, Cheng Wang, Meiqi Chang, Yan Huang, Yu Chen   +10 more
wiley   +1 more source

Boundary Integral Methods for Cavitation Bubbles Near Boundaries [PDF]

, 2001
The paper will review the art, craft and science of modelling cavitation bubbles near boundaries through the use of the boundary integral method. The presentation will come in four parts, namely, a discussion of recent experimental studies that have ...
Blake, J. R., Pearson, A., Pearson, Antony, Otto, Stephen, Otto, S. R., Blake, John   +5 more
core  

Cavitation-Enhanced Drug Delivery and Immunotherapy

, 2023
Cavitation-Enhanced Drug Delivery and Immunotherapy is a rapidly evolving area that has been buoyed in recent years by the development of methods harnessing the activity of ultrasound-stimulated bubbles, known as cavitation.

core   +1 more source