Results 21 to 30 of about 33,094 (123)
Veterinary Dermatology, Volume 33, Issue 4, Page 329-e77, August 2022., 2022 Background– Cannabidiol (CBD) and cannabidiolic acid (CBDA) are reported to have antinociceptive, immunomodulatory and anti‐inflammatory actions. Objectives – To determine if CBD/CBDA is an effective therapy for canine atopic dermatitis (cAD). Conclusions and clinical relevance – Cannabidiol/CBDA as an adjunct therapy decreased pruritus, and not skin ...
Melissa Loewinger +4 more
wiley +1 more source
Cytotoxic and hemolytic activities of extracts of the fish parasite dinoflagellate amyloodinium ocellatum [PDF]
, 2022 The dinoflagellate Amyloodinium ocellatum is the etiological agent of a parasitic disease named amyloodiniosis. Mortalities of diseased fish are usually attributed to anoxia, osmoregulatory impairment, or opportunistic bacterial infections ...
Fidalgo E Costa, Pedro +6 more
core +1 more source
Aging Cell, Volume 20, Issue 1, January 2021., 2021 Peripheral inflammation preceeding ischemic stroke impairs neuronal survival specifically in the elderly. This increased vulnerability is associated with downregulation of the expression of miR‐127, in both animals and humans. Our results reveal novel molecular targets for treating ischemic stroke, and underline the impact of peripheral inflammation on
Sanna Loppi +19 more
wiley +1 more source
HIGH BIOMAS BLOOMS CAUSING FISH KILLS AND OTHER ENVIRONMENTAL IMPACTS [PDF]
, 2023 Harmful algal blooms (HABs) have significant impacts on food safety and security through contamination or mass mortalities of aquatic organisms. Indeed, if not properly controlled, aquatic products contaminated with HAB biotoxins are responsible for ...
Cembella, Allan
core +1 more source
Current Research in Pharmacology and Drug Discovery, 2022 Neuronal dysfunction and subsequent apoptosis under high glucose conditions during diabetes contribute majorly to the manifestation of diabetic peripheral neuropathy (DPN). PERK (protein kinase RNA (PKR)-like ER kinase) one among the three canonical arms
Chayanika Gundu +4 more
semanticscholar +1 more source
DC electrical stimulation enhances proliferation and differentiation on N2a and MC3T3 cell lines
Journal of Biological Engineering, 2022 Background Electrical stimulation is a novel tool to promote the differentiation and proliferation of precursor cells. In this work we have studied the effects of direct current (DC) electrical stimulation on neuroblastoma (N2a) and osteoblast (MC3T3 ...
Daniel Martín +7 more
semanticscholar +1 more source
Veterinary Dermatology, Volume 31, Issue 2, Page 86-e8, April 2020., 2020 Background Canine pyoderma is a common skin infection caused predominantly by staphylococcal bacteria. Because of increasing rates of antimicrobial resistance in bacterial isolates, there is an urgent need for alternative or supplementary treatment options.
Wolfgang Bäumer +2 more
wiley +1 more source
A Shortage of FTH Induces ROS and Sensitizes RAS-Proficient Neuroblastoma N2A Cells to Ferroptosis
International Journal of Molecular Sciences, 2021 Ferroptosis, an iron-dependent form of programmed cell death, has excellent potential as an anti-cancer therapeutic strategy in different types of tumors, especially in RAS-mutated ones.
Ruiqing Lu +5 more
semanticscholar +1 more source
Dieckol Ameliorates Aβ Production via PI3K/Akt/GSK-3β Regulated APP Processing in SweAPP N2a Cell
Marine Drugs, 2021 The proteolytic processing of amyloid precursor protein (APP) by β-secretase (BACE1) and γ-secretase releases amyloid-β peptide (Aβ), which deposits in amyloid plaques and contributes to the initial causative events of Alzheimer’s disease (AD).
Jeong‐Hyun Yoon +7 more
semanticscholar +1 more source
Journal of Molecular Biology, 2021 Striated muscle responds to mechanical overload by rapidly up-regulating the expression of the cardiac ankyrin repeat protein, CARP, which then targets the sarcomere by binding to titin N2A in the I-band region.
Tiankun Zhou +14 more
semanticscholar +1 more source