Results 31 to 40 of about 33,094 (123)
Acúmulo e efeitos de toxinas de dinoflagelados bênticos em organismos marinhos, e possíveis interações com plástico marinho [PDF]
Orientador: Prof. Dr. Luiz Laureno Mafra JuniorCoorientadores: Prof. Dr. Paulo da Cunha Lana, Prof. Dr. Leonardo Sandrini NetoTese (doutorado) - Universidade Federal do Paraná, Campus Pontal do Paraná - Centro de Estudos do MarPrograma de Pós-Graduação ...
Leite, Isabel do Prado
core +1 more source
The titin N2B and N2A regions: biomechanical and metabolic signaling hubs in cross-striated muscles
Muscle specific signaling has been shown to originate from myofilaments and their associated cellular structures, including the sarcomeres, costameres or the cardiac intercalated disc.
R. J. van der Pijl +5 more
semanticscholar +1 more source
The N2A region of titin has a unique structural configuration
Stronczek et al. analyze the structure of the titin-N2A poly-Ig segment, a key signaling element in the sarcomere. They reveal a unique topography for the I81-I83 tandem, but they could not confirm the presence of Ca2+ binding sites in I81-I83 or the ...
Chiara Stronczek +6 more
semanticscholar +1 more source
Health economists are currently debating, with some suspicion, the relative merits of cost-benefit analysis (CBA), grounded in theoretical welfare economics, and the proliferation of social return on investment (SROI), a pragmatic approach of developing ...
R. Edwards, C. Lawrence
semanticscholar +1 more source
Desarrollo de métodos in vitro para la detección de biotoxinas emergentes en aguas europeas [PDF]
Traballo Fin de Grao en Veterinaria. Curso 2020-2021En los últimos años, el cambio climático y el exceso de gases de efecto invernadero en la atmósfera han hecho que la temperatura terrestre y oceánica haya aumentado, cambiando las características ...
Cao Cancelas, Alejandro
core
Development of bioanalytical devices for the detection of ciguatoxins and the ciguatoxin producing genera Gambierdiscus and Fukuyoa [PDF]
La ciguatera (CFP) és una intoxicació alimentària que provoca símptomes gastrointestinals, cardíacs i neurològics que poden durar setmanes, mesos o fins i tot anys.
Gaiani, Greta
core
Emerging toxins of European concern: identification, development of reference material and methods [PDF]
Phytoplankton is the autotrophic component of marine and freshwater ecosystems whose activity is crucial for the well-being of all the living organisms, including terrestrial and aquatic ones.
Varriale, Fabio
core
The Mediterranean diet is associated with health benefits due to bioactive compounds such as polyphenols. The biological activities of three polyphenols (quercetin (QCT), resveratrol (RSV), apigenin (API)) were evaluated in mouse neuronal N2a cells in ...
A. Yammine +10 more
semanticscholar +1 more source
Synaptic Dysfunction in Prion Diseases: A Trafficking Problem?
Synaptic dysfunction is an important cause of neurological symptoms in prion diseases, a class of clinically heterogeneous neurodegenerative disorders caused by misfolding of the cellular prion protein (PrPC). Experimental data suggest that accumulation of misfolded PrPC in the endoplasmic reticulum (ER) may be crucial in synaptic failure, possibly ...
Assunta Senatore +3 more
wiley +1 more source
Polyethylenimine (PEI), considered as the most potent and promising alternative carrier to viral vectors, has been studied as the “state of the art” among various polymers for nonviral gene delivery applications for many years. Although PEI‐based carrier minimizes the bottlenecks associated with viral vectors such as unwanted immunogenicity and ...
Chong-Su Cho, K. Hokamoto, A. O. Neto
wiley +1 more source

